Uterine metastasis from invasive ductal breast carcinoma: A case report with literature review
| Autor: | Camille Brochard, Anne-Sophie Bouvier, Eva Marchand, Nabilah Panchbhaya, Anne-Sophie Leveau-Vallier, Françoise Cornelis, Camille Mimoun, Matthieu Mezzadri, J.-L. Benifla |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Lobular carcinoma Breast Neoplasms Hysterectomy Asymptomatic Metastasis 03 medical and health sciences 0302 clinical medicine Breast cancer medicine Humans skin and connective tissue diseases Lymph node 030219 obstetrics & reproductive medicine medicine.diagnostic_test business.industry Carcinoma Ductal Breast Obstetrics and Gynecology Metrorrhagia Middle Aged medicine.disease medicine.anatomical_structure Reproductive Medicine Positron emission tomography 030220 oncology & carcinogenesis Uterine Neoplasms Female Radiology medicine.symptom business |
| Zdroj: | Journal of Gynecology Obstetrics and Human Reproduction. 50:101993 |
| ISSN: | 2468-7847 |
| Popis: | Breast cancer is the leading cause of cancer death in women, and most breast cancer related deaths are due to metastases. Uterine metastases from breast cancer are uncommon and rarely reported in the literature. We described the case of a 50 years-old-woman who developed a uterine metastasis, 6 years after the diagnosis of an invasive ductal breast carcinoma. Indeed, although the patient was asymptomatic, the monitoring imaging examinations, particularly the computed tomography (CT) and the positron emission tomography/computed tomography (PET/CT), showed a myometrial lesion. Non-conservative total hysterectomy was performed. The anatomo-pathological examination revealed a myometrial metastasis from an invasive ductal breast carcinoma. Seventeen months after surgery, the patient had no pelvic recurrence, but lungs and bones metastases progressed despite chemotherapy. In the lack of guidelines of uterine metastases from breast cancer's management, we reviewed the existing literature with the aim to provide a rational framework for clinical presentation, diagnostic approach, histological findings and treatment of this rare and heterogeneous pathology. Uterine metastases of breast cancer are frequently revealed with metrorrhagia. They occur preferentially in tumours with initial lobular carcinoma, initial lymph node involvement and positive hormonal receptors. |
| Databáze: | OpenAIRE |
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