Nonfunctioning argyrophilic tumor (APUDoma) of the hepatic duct: simplified methods of detecting biogenic amines in tissue
| Autor: | P. S. Dickman, D. M. Judge, S. Trapukdi |
|---|---|
| Rok vydání: | 1976 |
| Předmět: |
Adult
Male Simplified methods Staining and Labeling Decarboxylation Carcinoma Liver Neoplasms Neural crest Foregut Hepatic Duct Common General Medicine Biology Apudoma medicine.disease Cytoplasmic Granules medicine.anatomical_structure Biochemistry Microscopy Fluorescence Endocrine neoplasm medicine Endocrine system Humans Duct (anatomy) |
| Zdroj: | American journal of clinical pathology. 66(1) |
| ISSN: | 0002-9173 |
| Popis: | This report documents a foregut endocrine neoplasm in an unusual location, the main hepatic bile duct, and describes simplified methods of detecting similar endocrine tumors. Formaldehyde fume-induced fluorescence (FIF) is a quick, specific method to demonstrate biogenic amines. FIF combined with histochemical procedures showing abundant alpha-glycerol phosphate dehydrogenase and esterases indicates the neural crest origin of these and related neoplasms. Amine precursor uptake and decarboxylation (APUD) is a significant marker of these cells and gives them their name. |
| Databáze: | OpenAIRE |
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