| Autor: |
Wenger, Kathrin, Viode, Arthur, Schlaffner, Christoph N., van Zalm, Patrick, Cheng, Long, Dellovade, Tammy, Langlois, Xavier, Bannon, Anthony, Chang, Rui, Connors, Theresa R., Oakley, Derek, Renard, Bernhard, Rappsilber, Juri, Hyman, Bradley, Steen, Hanno, Steen, Judith A. |
| Rok vydání: |
2023 |
| DOI: |
10.6084/m9.figshare.22602073 |
| Popis: |
Additional file 3. Figure S3. PTM analyses of pathological Tau during the progression in P301S and P301L mouse models. A, C Euclidean hierarchical clustering of binary PTMs data from pathological Tau derived from the P301S brain stem (A) and subcortical region (C). B, D Euclidean hierarchical clustering of binary PTMs data from pathological Tau derived from the P301L hippocampus (B) and subcortical region (D). PTMs that were used for clustering were found in at least 50% of the biological replicates in at least one time point. Grey squares indicate the presence of a PTM. Annotated clusters represent PTMs identified at all time points (blue), pathological PTMs appearing with tangle formation (orange) and PTMs appearing before (yellow) or after (magenta) the onset of tangle formation. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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