Sensitivity and specificity of breast cancer ICD-9-CM codes in three Italian administrative healthcare databases: a diagnostic accuracy study
| Autor: | Marcello De Giorgi, Paola Casucci, Ettore Bidoli, Gianni Giovannini, Francesco Cozzolino, Paolo Collarile, Iosief Abraha, Massimiliano Orso, Rita Chiari, Diego Serraino, Mario Fusco, Alessandro Montedori, Fabrizio Stracci, Jennifer Foglietta, Maria Francesca Vitale, Annalisa Granata, Walter Orlandi |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Adult
validity Databases Factual administrative database breast cancer sensitivity and specificity Medicine (all) Diagnostic accuracy Breast Neoplasms computer.software_genre Sensitivity and Specificity 03 medical and health sciences 0302 clinical medicine Breast cancer International Classification of Diseases Research Methods medicine Carcinoma Humans 030212 general & internal medicine Database business.industry Carcinoma in situ Medical record Research Clinical Coding Cancer General Medicine Middle Aged medicine.disease Logistic Models Italy Nodular lesions 030220 oncology & carcinogenesis Female Breast carcinoma business computer |
| Zdroj: | BMJ Open |
| ISSN: | 2044-6055 |
| Popis: | ObjectivesTo assess the accuracy of International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes in identifying patients diagnosed with incident carcinoma in situ and invasive breast cancer in three Italian administrative databases.DesignA diagnostic accuracy study comparing ICD-9-CM codes for carcinoma in situ (233.0) and for invasive breast cancer (174.x) with medical chart (as a reference standard). Case definition: (1) presence of a primary nodular lesion in the breast and (2) cytological or histological documentation of cancer from a primary or metastatic site.SettingAdministrative databases from Umbria Region, Azienda Sanitaria Locale (ASL) Napoli 3 Sud (NA) and Friuli VeneziaGiulia (FVG) Region.ParticipantsWomen with breast carcinoma in situ (n=246) or invasive breast cancer (n=384) diagnosed (in primary position) between 2012 and 2014.Outcome measuresSensitivity and specificity for codes 233.0 and 174.x.ResultsFor invasive breast cancer the sensitivities were 98% (95% CI 93% to 99%) for Umbria, 96% (95% CI 91% to 99%) for NA and 100% (95% CI 97% to 100%) for FVG. Specificities were 90% (95% CI 82% to 95%) for Umbria, 91% (95% CI 83% to 96%) for NA and 91% (95% CI 84% to 96%) for FVG.For carcinoma in situ the sensitivities were 100% (95% CI 93% to 100%) for Umbria, 100% (95% CI 95% to 100%) for NA and 100% (95% CI 96% to 100%) for FVG. Specificities were 98% (95% CI 93% to 100%) for Umbria, 86% (95% CI 78% to 92%) for NA and 90% (95% CI 82% to 95%) for FVG.ConclusionsAdministrative healthcare databases from Umbria, NA and FVG are accurate in identifying hospitalised news cases of carcinoma of the breast. The proposed case definition is a powerful tool to perform research on large populations of newly diagnosed patients with breast cancer. |
| Databáze: | OpenAIRE |
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