Improving clinical descriptions to understand the effects of dementia treatment: consensus recommendations
| Autor: | Kenneth Rockwood, Christine Joffres on behalf of the Halifax Co |
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| Rok vydání: | 2002 |
| Předmět: |
Clinical Trials as Topic
Psychotherapist business.industry Consensus conference medicine.disease Psychiatry and Mental health Future study Treatment Outcome Quality of life (healthcare) Alzheimer Disease Quality of Life medicine Humans Dementia Antidementia drug Narrative Cholinesterase Inhibitors Geriatrics and Gerontology business Neuroscience Aged Qualitative research |
| Zdroj: | International Journal of Geriatric Psychiatry. 17:1006-1011 |
| ISSN: | 1099-1166 0885-6230 |
| DOI: | 10.1002/gps.733 |
| Popis: | Objectives To recommend how the description of clinically detectable treatment effects might be improved for antidementia drug trials. Method Consensus conference, with review of available evidence. Results We suggest widespread, systematic, qualitative studies, based on prospective observations such as the clinicians' narrative descriptions of patient's changes used in the Clinician's Interview-Based Impressions of Change (CIBIC-Plus), plus caregiver input. The identification of patient and caregiver expectations, and an understanding of how these expectations are met, are proposed as priorities for future study. Conclusion Better descriptions of treatment effects can enhance our understanding of both clinical meaningfulness and cholinergic function in the brain. Copyright © 2002 John Wiley & Sons, Ltd. |
| Databáze: | OpenAIRE |
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