Divergent Effects of Beta-Blocker Therapy on Self-Estimated and Objectively Scored Activities of Daily Living
| Autor: | Yorio Kimura, Koshiro Fukiyama, Tomomasa Kamiyama, Teruo Omae, Hiromi Muratani |
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| Rok vydání: | 1999 |
| Předmět: |
Male
medicine.medical_specialty Scoring system Activities of daily living Physiology Adrenergic beta-Antagonists Cognition Mental Processes Quality of life Activities of Daily Living Internal Medicine Humans Medicine In patient Medical prescription skin and connective tissue diseases Elderly patient Aged business.industry Beta blocker therapy Follow up studies humanities Hypertension Physical therapy Female sense organs Cardiology and Cardiovascular Medicine business human activities Follow-Up Studies |
| Zdroj: | Hypertension Research. 22:85-93 |
| ISSN: | 1348-4214 0916-9636 |
| DOI: | 10.1291/hypres.22.85 |
| Popis: | To identify factors that influence changes in the activities of daily living (ADL) assessed by a standardized scoring system, ADL-20, and factors affecting the self-estimate of the changes in ADL, we conducted a 1-yr follow-up study of 1,163 outpatients aged 50 yr or older. The follow-up rate was 83.1%. A decrease in the ADL score was associated with advancing age and a lower prescription rate of beta-blockers. Analysis of the modalities of ADL revealed an association between a decreasing mobility score and a lower prescription rate of beta-blockers. In patients with impaired ADL at the time of enrollment, worsening of the ADL score was also associated with a lower baseline ADL score and a history of cardiovascular events. The prescription rate of diuretics was lower in patients who exhibited an improvement in ADL score. There was a considerable dissociation between the self-estimate of changes in ADL and the actual change in ADL-20 score. In more than 60% of patients with impaired baseline ADL, the self-estimate of changes was worse than the actual change in the ADL score. The "worse-than-actual" self-estimate of changes in ADL was associated with a higher prescription rate of beta-blockers. Thus, a history of cardiovascular events accelerates the aging-related deterioration of ADL. The use of a beta-blocker may worsen the self-estimate of the changes in ADL, while the actual ADL is preserved or slightly improved during beta-blocker therapy. |
| Databáze: | OpenAIRE |
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