Ultrasonography as an objective tool for assessment of infantile hemangioma treatment with propranolol
| Autor: | Daniel Menezes Silvestre, Glaucia Helena de Oliveira Labinas, Juliana Gobbi Alvarenga, Maria Cecília Rivitti-Machado, Zilda Najjar Prado de Oliveira, Marcio Bouer, Paulo Santos, Anita Rotter, Luciana Paula Samorano |
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| Rok vydání: | 2016 |
| Předmět: |
Male
medicine.medical_specialty Skin Neoplasms Adrenergic beta-Antagonists Dermatology Propranolol 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Neoplastic Syndromes Hereditary 030225 pediatrics Infantile hemangioma Photography Tumor regression Humans Medicine Volume reduction Hemangioma Capillary Retrospective Studies Ultrasonography Tumor size business.industry Infant Retrospective cohort study Surgery Treatment Outcome Vascular Tumors Child Preschool Female Radiology business medicine.drug |
| Zdroj: | International Journal of Dermatology. 56:190-194 |
| ISSN: | 0011-9059 |
| DOI: | 10.1111/ijd.13442 |
| Popis: | Background Infantile hemangiomas (IHs) are the most common benign vascular tumors of childhood. Propranolol is an effective drug in treating IH. A reliable and complementary instrument is necessary to evaluate IH response to propranolol in addition to clinical and photographic assessments. Ultrasonography is a simple and non-invasive technique that enables precise measurements of tumor size and contributes to objective follow-up. Objective To demonstrate the use of serial ultrasonography as an adjunctive tool for assessment of IH treatment with propranolol. Patients and methods A retrospective study of 19 patients with IH treated with propranolol was conducted from January 2009 to March 2014. Data of individual IH volume at the beginning and at least 6 months after the onset of treatment and overall volume reduction by ultrasonographic measurement were obtained. Results We observed a statistically significant IH volume reduction of approximately 0.51 cm3. This volume corresponds to an average reduction of 47% in the final volume compared with the initial volume. Conclusion Ultrasonographic measurements contribute to demonstrate tumor regression and IH response to propranolol. Thus, ultrasonography is an important instrument to guide therapeutic strategies. |
| Databáze: | OpenAIRE |
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