Wegener granulomatosis – an atypical case
| Autor: | Bernard S. Kaplan, Kevin E.C. Meyers, Madhura Pradhan, Marta Guttenberg |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Pathology
medicine.medical_specialty Tuberculosis Adolescent Biopsy Kidney Glomerulus Pulmonary Artery Methylprednisolone Diagnosis Differential medicine Humans Cyclophosphamide Lung medicine.diagnostic_test business.industry Granulomatosis with Polyangiitis medicine.disease Kidney Transplantation medicine.anatomical_structure Respiratory failure Nephrology Pediatrics Perinatology and Child Health Prednisone Female Radiography Thoracic Pulmonary hemorrhage Differential diagnosis Tomography X-Ray Computed Vasculitis business Kidney disease |
| Zdroj: | Pediatric Nephrology. 14:862-871 |
| ISSN: | 1432-198X 0931-041X |
| Popis: | An unusual sequence of the clinical manifestations of microvascular disease is described in a 15 year-old girl. She initially presented with acute renal failure caused by a crescentic glomerulonephritis associated with positive tests for MPO-ANCA. Eighteen months later she had pulmonary hemorrhage and respiratory failure. An open lung biopsy showed granulomas that were diagnostic for Wegener granulomatosis. We discuss the diagnostic dilemmas faced in attempts to distinguish infective causes of pulmonary granulomas, such as tuberculosis or fungi, from granulomas associated with vasculitis, in a patient previously treated with immunosuppressive therapy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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