Prognosis of the neurological complications of acute hypernatraemia
| Autor: | R.C. Evans, P.H. Morris-Jones, I.B. Houston |
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| Rok vydání: | 1967 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Intelligence Infarction Neurological examination Seizures medicine Neurological syndrome Humans Urea Child Depression (differential diagnoses) Neurologic Examination Hypernatremia medicine.diagnostic_test Acute hypernatraemia business.industry Sodium Infant Newborn Infant Electroencephalography General Medicine Muscular hypertonicity Intelligence testing medicine.disease Prognosis Surgery Regimen Child Preschool Female Nervous System Diseases business Follow-Up Studies |
| Zdroj: | Lancet (London, England). 2(7531) |
| ISSN: | 0140-6736 |
| Popis: | 18 (36%) of a series of 50 cases of acute hypernatraemia had a neurological syndrome which included convulsions, muscular hypertonicity, and depression of consciousness. This syndrome was commoner with higher levels of either serum-sodium or blood-urea, but the data suggest that serum osmolality may be the most significant factor. The initial mortalityrate was 20%. Of the 40 survivors, 32 could be examined: 12 (37%) of these had abnormalities on neurological examination, intelligence testing, or electroencephalography; in several, however, the abnormalities were probably unrelated to the earlier hypernatraemia, and only 3 out of 32 (9%) had both related and symptomatically important lesions. This suggests that, in some instances, convulsions were caused by transient cerebral oedema rather than by infarction or haemorrhage, and may therefore be preventable by improvement of the regimen of rehydration. |
| Databáze: | OpenAIRE |
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