Acanthamoebiasis in a Dog

Autor: K. M. Ayers, L. H. Billups, F. M. Garner
Rok vydání: 1972
Předmět:
Zdroj: Veterinary Pathology. 9:221-226
ISSN: 1544-2217
0300-9858
DOI: 10.1177/030098587200900305
Popis: Acanthamoeba infection occurred in a 4-year-old military working dog (German shepherd). The disease was manifested by multifocal necrohemorrhagic foci in the heart, lungs, liver, and pancreas. Numerous organisms morphologically compatible with Acanthamoeba sp. were seen in the lesions. The infection may have been caused by local invasion of a wound and hematogenous spread, via the respiratory tract, by inhalation of the organisms, or by direct extension of an inapparent nasal infection. The status of the amoeba genera Acanthamoeba and Hartmannella was uncertain for many years, and some taxonomists placed them both in the genus Hartmannella. The literature reflected these uncertainties, and several authors used one of the terms and added the other in parentheses. In 1968 the distinction between the two organisms was clarified and is now accepted by most taxonomists. The distinction was based on multiple characters, including the morphology of cysts and pseudopodia, manner of locomotion, and nutritional requirements (6, 71. In addition, although Acanthamoeba has been shown to be pathogenic experimentally, there is no evidence that Hartmannella species, as it is now defined, can cause disease recognizable in tissue sections. Acanthamoeba sp. is found in soil in both vegetative and cystic forms, where they feed on bacteria, yeasts, fungi, and other organic matter (4). In 1957 Acanthamoeba organisms were discovered in cultures of monkey kidney cells (5). The origin of the contaminating amoeba was not known. In 1959 it was demonstrated that Acanthamoeba could produce a meningoencepha- litis when injected intranasally in mice and monkeys (2). A recent report described a naturally occurring case of hartmannellosis in a bull (6). Using
Databáze: OpenAIRE
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