Patient age and risk of recurrence of primary melanoma at high risk of spread
| Autor: | Kiarash Khosrotehrani, L. A. von Schuckmann, Reza Ghiasvand, Bernard Mark Smithers, Vanessa L. Beesley, Adèle C. Green, M. C. Hughes, M. Malt |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Skin Neoplasms business.industry Melanoma MEDLINE Dermatology medicine.disease Delayed diagnosis Immune surveillance Comorbidity 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Patient age Internal medicine medicine Humans Neoplasm Recurrence Local business |
| Zdroj: | The British journal of dermatologyReferences. 184(3) |
| ISSN: | 1365-2133 |
| Popis: | Melanoma is more aggressive with poorer outcomes in older than younger patients. Older age has been associated with greater tumour thickness, higher rates of ulceration, and high mitotic rates, but it is not clear whether poorer outcomes in the elderly are solely due to these tumour-specific features or to additional effects of age-related decline in in immune surveillance, greater comorbidity, and age-related behaviours such as delayed diagnosis. |
| Databáze: | OpenAIRE |
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