Cardiovascular Effects of Tramadol in Dogs Anesthetized with Sevoflurane

Autor: Kazuto Yamashita, Takaharu Itami, Hiroki Inoue, Mohammed A. Umar, Jun Tamura, Naomichi Tamaru, Kodai Kawase, Tomohito Ishizuka, Kenjirou Miyoshi
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: The journal of veterinary medical science. 73(12):1603-1609
Popis: Cardiovascular effects of tramadol were evaluated in dogs anesthetized with sevoflurane. Six beagle dogs were anesthetized twice at 7 days interval. The minimum alveolar concentration (MAC) of sevoflurane was earlier determined in each dog. The dogs were then anesthetized with sevoflurane at 1.3 times of predetermined individual MAC and cardiovascular parameters were evaluated before (baseline) and after an intravenous injection of tramadol (4 mg/kg). The administration of tramadol produced a transient and mild increase in arterial blood pressure (ABP) (P=0.004) with prolonged increase in systemic vascular resistance (SVR) (P
Databáze: OpenAIRE