Cardiovascular Effects of Tramadol in Dogs Anesthetized with Sevoflurane
Autor: | Kazuto Yamashita, Takaharu Itami, Hiroki Inoue, Mohammed A. Umar, Jun Tamura, Naomichi Tamaru, Kodai Kawase, Tomohito Ishizuka, Kenjirou Miyoshi |
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Jazyk: | angličtina |
Rok vydání: | 2011 |
Předmět: |
Male
Methyl Ethers tramadol Minimum alveolar concentration Cardiac output sevoflurane canine Blood Pressure Sevoflurane Dogs Heart Rate medicine Animals Pulmonary wedge pressure General Veterinary business.industry Central venous pressure Analgesics Opioid Blood pressure medicine.anatomical_structure Vasoconstriction Anesthesia Anesthetics Inhalation Vascular resistance Drug Therapy Combination Female medicine.symptom business cardiovascular effects medicine.drug |
Zdroj: | The journal of veterinary medical science. 73(12):1603-1609 |
Popis: | Cardiovascular effects of tramadol were evaluated in dogs anesthetized with sevoflurane. Six beagle dogs were anesthetized twice at 7 days interval. The minimum alveolar concentration (MAC) of sevoflurane was earlier determined in each dog. The dogs were then anesthetized with sevoflurane at 1.3 times of predetermined individual MAC and cardiovascular parameters were evaluated before (baseline) and after an intravenous injection of tramadol (4 mg/kg). The administration of tramadol produced a transient and mild increase in arterial blood pressure (ABP) (P=0.004) with prolonged increase in systemic vascular resistance (SVR) (P |
Databáze: | OpenAIRE |
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