Are tonsils a reservoir for Helicobacter pylori infection in children?
| Autor: | Bülent Topuz, Akile Sarıoğlu Büke, Ilknur Kaleli, Cüneyt Orhan Kara, Melek Demir, Mustafa Yilmaz, Funda Tümkaya |
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| Rok vydání: | 2004 |
| Předmět: |
Disease reservoir
bacterial colonization Adenoidectomy Adenoids/*microbiology Blood/microbiology Child Child Preschool Disease Reservoirs Feces/microbiology Female Helicobacter Infections/diagnosis Helicobacter pylori/*isolation & purification Humans Male Palatine Tonsil/*microbiology Prospective Studies Tonsillectomy Tonsillitis/microbiology/surgery Palatine Tonsil Tonsillitis Palatine tonsil Feces antibody detection Serological test antibody tonsillectomy analytic method child clinical article education.field_of_study adenoid biology article Antibody titer General Medicine Tonsils enzyme immunoassay Blood female medicine.anatomical_structure priority journal Gastritis medicine.symptom adenotonsillectomy venous blood Population Adenoid antibody titer Helicobacter Infections Helicobacter infection antigen male Stool antigen medicine feces analysis controlled study human education Helicobacter pylori business.industry bacterial infections and mycoses medicine.disease biology.organism_classification Otorhinolaryngology tonsil Adenoids Pediatrics Perinatology and Child Health Immunology H. pylori tonsils serological test stool antigen business |
| Zdroj: | International Journal of Pediatric Otorhinolaryngology. 68:307-310 |
| ISSN: | 0165-5876 |
| DOI: | 10.1016/j.ijporl.2003.10.016 |
| Popis: | Objective: Helicobacter pylori (H. Pylori) has been associated with the development of gastritis, peptic ulcer and gastric cancer. Although H. pylori infects up to more than half of the world's population, to date the precise modes of transmission has not been fully understood yet. Therefore a study was planned to investigate whether the tonsils and the adenoid tissue were the reservoir or the gate for the entrance of H. pylori. Methods: The adenotonsillectomy specimens obtained from 50 children, between two and 10 years of age were examined for H. Pylori colonization by the CLO-test method. Before tonsillectomy, anti-H. pylori IgG antibody titers were detected by commercial enzyme immunoassay method in venous blood and H. pylori antigen enzyme immunoassay for detection of H. pylori in stool was used to define current infection status. Results: The stool antigen was positive in 25 (50%) of 50 children. Serum IgG antibody was positive in 28 (56%) patients and both tests were positive in 21 (42%) patients. H. pylori positivity was not detected in any one of the adenotonsillectomy specimens with the CLO-test method. Conclusion: In this study although H. pylori was detected in stools of children, it was not detected in adenotonsillectomy specimens with CLO-test method. The results may indicate that H. pylori does not colonize in either adenoid or tonsils and that these tissues do not constitute a reservoir for H. pylori infection. (C) 2003 Elsevier Ireland Ltd. All rights reserved. C1 Pamukkale Univ, Fac Med, Dept Gastroenterol, Denizli, Turkey. Pamukkale Univ, Fac Med, Dept Otorhinolaryngol, Denizli, Turkey. Pamukkale Univ, Fac Med, Dept Microbiol & Clin Microbiol, Denizli, Turkey. Pamukkale Univ, Fac Med, Dept Pediat Surg, Denizli, Turkey. |
| Databáze: | OpenAIRE |
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