Chemical composition and antifungal activity of the essential oil of Varronia schomburgkii (DC.) Borhidi (Cordiaceae) from plants cultivated in French Guiana
| Autor: | Pauline Burger, Denis Blanchet, Mehdi Khodjet el Khil, Xavier Fernandez, Marine Ginouves, Piero G. Delprete, Ghislaine Prévot, Camille Inès Scotto |
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| Přispěvatelé: | Institut de Chimie de Nice (ICN), Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA), Ecosystemes Amazoniens et Pathologie Tropicale (EPat), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Guyane (UG), Botanique et Modélisation de l'Architecture des Plantes et des Végétations (UMR AMAP), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut National de la Recherche Agronomique (INRA)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud]), Oleaflore, Conseil Régional de la Guyane, University of French Guiana, ANR-10-LABX-0025,CEBA,CEnter of the study of Biodiversity in Amazonia(2010), European Project: 31454,FEDER- Presage, Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Institut National de la Recherche Agronomique (INRA)-Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut de Recherche pour le Développement (IRD [France-Sud]), Université Nice Sophia Antipolis (... - 2019) (UNS), Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS), Epidemiologie des Parasitoses Tropicales (EPaT Team), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université des Antilles et de la Guyane (UAG), ANR-10-LABX-25-01/10-LABX-0025,CEBA,CEnter of the study of Biodiversity in Amazonia(2010) |
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0106 biological sciences
Antifungal medicine.drug_class Leishmania guyanensis Chemical composition [SDV.BID.SPT]Life Sciences [q-bio]/Biodiversity/Systematics Phylogenetics and taxonomy 010603 evolutionary biology 01 natural sciences Varronia schomburgkii law.invention [SDV.EE.ECO]Life Sciences [q-bio]/Ecology environment/Ecosystems law Botany medicine chemical composition Candida albicans Essential oil Candida spp activities biology General Chemistry [SDV.BV.BOT]Life Sciences [q-bio]/Vegetal Biology/Botanics biology.organism_classification Antimicrobial anti-leishmanial potency 0104 chemical sciences French Guiana 010404 medicinal & biomolecular chemistry Cordiaceae Antifungal activities Anti-leishmanial potency [SDE.BE]Environmental Sciences/Biodiversity and Ecology antifungal |
| Zdroj: | Journal of Essential Oil Research Journal of Essential Oil Research, 2017, 29 (4), pp.304-312. ⟨10.1080/10412905.2017.1278729⟩ Journal of Essential Oil Research, Taylor & Francis, 2017, 29 (4), pp.304-312. ⟨10.1080/10412905.2017.1278729⟩ |
| ISSN: | 1041-2905 |
| DOI: | 10.1080/10412905.2017.1278729⟩ |
| Popis: | International audience; This study reports for the first time the chemical composition of the essential oil of Varronia schomburgkii (DC.) Borhidi cultivated in French Guiana. This essential oil was examined by a combination of GC/FID and GC-MS techniques and was further tested for antifungal activity against several Candida strains, as well as for anti-leishmanial activity against the reference strain Leishmania guyanensis. A total of 45 components accounting for 93.61% of the total GC/FID chromatogram were identified. The essential oil is dominated by sesquiterpenes and oxygenated sesquiterpenes among which ?-caryophyllene (46.99 ± 0.32%) is the major one. No anti-leishmania activity could be assessed, while a strong antimicrobial activity of this essential oil was evidenced in vitro against a Candida albicans strain by the definition of a MIC value of 250 ?g/mL. V. schomburgkii essential oil might hence be considered in the future for the development of natural antifungal agents. |
| Databáze: | OpenAIRE |
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