Mathematical modeling and projection of Vitamin D levels before and during COVID-19: A cross-sectional study including 86.772 samples

Autor: Mehmet Emin Arayici, Sila Ovgu Korkut-Uysal, Asim Leblebici, Zeynep Akcali, Deniz Tuna Edizer, Seher Kabul, Dilek Cimrin, Ender Berat Ellidokuz
Rok vydání: 2022
DOI: 10.21203/rs.3.rs-1788872/v1
Popis: Purpose Vitamin D (Vit-D) is defined as a steroid hormone produced in the body by exposure of the human skin to UV (ultraviolet) B rays and has an important role in calcium and phosphorus metabolism as well as bone mineralization. In this study, it was aimed to examine Vit-D deficiency not only biologically but also mathematically and produce a mathematical model to determine the level of Vit-D if the COVID-19 measures continue. Methods This study included 86.772 patient samples. Vit-D levels have a wave-curved form. Mathematical modeling has been done for such a curve, and this model has been defined. For describing the model, the MATLAB Curve Fitting Toolbox has been used. SSE has been optimized by the Trust-Region algorithm where all the other parameters are selected as default. Results There was no significant difference between the sexes according to Vit-D levels (p > .05). It was determined that Vit-D levels were significantly higher in the summer months and lower in the winter months (p
Databáze: OpenAIRE