Low oxytocin levels are related to alexithymia in anorexia nervosa

Autor:	Reitumetse L Pulumo, Elizabeth A. Lawson, Nouchine Hadjikhani, Franziska Plessow, Dean A. Marengi, Kamryn T. Eddy, Lisseth Silva, Emily K. Gray, Debra L. Franko, Cindy Schmelkin, Jennifer J. Thomas, Karen K. Miller
Rok vydání:	2017
Předmět:	Adult medicine.medical_specialty Anorexia Nervosa Adolescent media_common.quotation_subject Oxytocin Article Young Adult 03 medical and health sciences Toronto Alexithymia Scale 0302 clinical medicine Alexithymia medicine Humans Personality Affective Symptoms Psychiatry media_common medicine.diagnostic_test Social anxiety Middle Aged medicine.disease 030227 psychiatry Psychiatry and Mental health Feeling Anorexia nervosa (differential diagnoses) Female medicine.symptom Psychology Weight gain hormones hormone substitutes and hormone antagonists 030217 neurology & neurosurgery medicine.drug
Zdroj:	International Journal of Eating Disorders. 50:1332-1338
ISSN:	0276-3478
DOI:	10.1002/eat.22784
Popis:	Objective Anorexia nervosa is associated with social-emotional functioning deficits and low levels of the social neurohormone oxytocin, even after weight gain. The relationship between low oxytocin levels and social-emotional functioning impairment has not been studied. Method We performed a cross-sectional study of 79 women (19 who were less than 85% of ideal body weight [IBW] with anorexia nervosa [AN], 26 who were 90–120% IBW with a history of AN [AN-WR], and 34 who were 90–120% IBW with no eating disorder history [H]). We administered the Eating Disorder Examination–Questionnaire (EDE-Q), Leibowitz Social Anxiety Scale–Self Report (LSAS-SR), Dimensional Assessment of Personality Pathology–Basic Questionnaire (DAPP-BQ; suspiciousness and insecure attachment subscales), and the Toronto Alexithymia Scale (TAS-20). We also analyzed fasting serum oxytocin levels. Results Most measures of social-emotional functioning showed impairment in women with AN and AN-WR compared to H. Oxytocin levels were low in AN-WR compared to H. Across groups, low oxytocin levels were associated with difficulty identifying feelings (r = −.45, p = .008) and overall alexithymia (r = −.34, p = .0489). Discussion We speculate that low oxytocin levels may contribute to alexithymia in women with anorexia nervosa.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e40d991b808dd023d2d0ba63fb740408 https://doi.org/10.1002/eat.22784 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.