Knee joint alterations in Zucker Diabetic Fatty (ZDF) rats in situ and the response of ZDF-rat derived articular chondrocytes exposed to TNF α in vitro

Autor: Shi, J, Kokozidou, M, Gögele, C, Meric, C, Schulze-Tanzil, G
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2021); 20211026-20211029; Berlin; DOCAB94-625 /20211026/
DOI: 10.3205/21dkou687
Popis: Objectives: Meanwhile a link between OA and type 2 diabetes mellitus (T2DM) has been strongly suggested. However, the shared pathogenetic mechanisms remain unclear. The aims of this study were (1) to assess whether early onset OA features are detectable in Zucker Diabetes Fatty (ZDF) rats which clinically [for full text, please go to the a.m. URL]
Databáze: OpenAIRE