Complete Resection of Pancreatoblastoma With Portal Vein Obstruction After High-dose Chemotherapy: A Case Report
| Autor: | Takaharu Oue, Takehisa Ueno, Souji Ibuka, Hiroomi Okuyama, Yoshiko Hashii, Takako Miyamura, Shuichiro Uehara |
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| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Vincristine Cyclophosphamide medicine.medical_treatment Pirarubicin Pancreatoblastoma Disease-Free Survival 03 medical and health sciences Pancreatectomy 0302 clinical medicine 030225 pediatrics Antineoplastic Combined Chemotherapy Protocols Biopsy medicine Humans Cisplatin Chemotherapy medicine.diagnostic_test Portal Vein business.industry Remission Induction Hematology medicine.disease Combined Modality Therapy Surgery Pancreatic Neoplasms Venous Insufficiency Oncology Child Preschool 030220 oncology & carcinogenesis Pediatrics Perinatology and Child Health Female business medicine.drug |
| Zdroj: | Journal of Pediatric Hematology/Oncology. 39:e275-e278 |
| ISSN: | 1077-4114 |
| DOI: | 10.1097/mph.0000000000000842 |
| Popis: | Background As no standard chemotherapy exists for pancreatoblastoma (PB), surgical resection is the most effective way of achieving complete remission. Case report A 3-year-old girl with PB causing portal vein obstruction was referred to our hospital. Because of the portal vein involvement, she initially received 5 cycles of preoperative chemotherapy after biopsy, consisting of cyclophosphamide, vincristine, pirarubicin, and cisplatin. After chemotherapy, she underwent distal pancreatectomy, and the tumor was resected completely. She has been disease free for 4 years since the operation. Conclusions Even in cases of advanced PB, complete surgical resection with appropriate chemotherapy can lead to complete remission. |
| Databáze: | OpenAIRE |
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