Vitamin e supplementation with rauwolfia vomitoria root bark extract improves hematological indices
| Autor: | Otitoju Olawale, Uwah Anthony Fidelis, Ufot Usenobong Friday, Akpanabiatu Monday Isaiah, Edet Emmanuel Effiong, Ndem Jessie Idongesit |
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| Rok vydání: | 2012 |
| Předmět: |
Antioxidant
Traditional medicine business.industry Vitamin E medicine.medical_treatment Vitamin e supplementation Hematological indices Immunity General Medicine complex mixtures visual_art visual_art.visual_art_medium medicine Bark Original Article Medicinal therapeutics business Vitamin supplementation Rauwolfia vomitoria |
| Zdroj: | North American Journal of Medical Sciences |
| ISSN: | 1947-2714 |
| Popis: | Background: Vitamin supplementation in Rauwolfia vomitoria root bark extract administration may interact and impact significantly on hematology of albino Wistar rats. Aim: In this investigation we studied vitamin E supplementation with Rauwolfia vomitoria root bark extract on the hematology of experimental animals. Materials and Methods: Forty two rats weighing 200 – 230 g were randomly selected into six groups of seven animals each. Group 1 animals serve as controls; group 2 received vitamin E (10 IU/kg body weight). Groups 3 and 4 were given the extract (150 and 300 mg/kg body weight) respectively. Groups 5 and 6 were given vitamin E (10 IU/kg body weight), the extract (150 and 300 mg/kg body weight) respectively. The extract and the vitamin were administered daily by oral intubation. Blood samples analyzed for hematological indices. Results: Decrease in white blood cell count (WBC) was observed, indicating improved immunity of animals. Extract at 150 and 300 mg/kg body weight with and without vitamin E affected hemoglobin and packed cell volume. Conclusion: Rauwolfia vomitoria with or without vitamin E improved animal's immunity and enhances their hematology. Interaction of vitamin E with the extract affects medicinal therapeutics of this plant. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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