Determining the count median diameter of nanoaerosols by simultaneously measuring their number and lung deposited surface area concentrations

Autor: Dominique Thomas, Olivier Witschger, Sébastien Bau, François Gensdarmes
Přispěvatelé: Laboratoire de Métrologie des Aérosols, Département Métrologie des Polluants (MP), Institut national de recherche et de sécurité (Vandoeuvre lès Nancy) (INRS ( Vandoeuvre lès Nancy))-Institut national de recherche et de sécurité (Vandoeuvre lès Nancy) (INRS ( Vandoeuvre lès Nancy)), Institut de Radioprotection et de Sûreté Nucléaire (IRSN), Laboratoire Réactions et Génie des Procédés (LRGP), Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS), Institut national de recherche et de sécurité (Vandoeuvre lès Nancy) (INRS ( Vandoeuvre lès Nancy)), Centre National de la Recherche Scientifique (CNRS)-Université de Lorraine (UL)
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Nanoaerosol
Materials science
Nanoparticle measurement method
Instrumentation
Analytical chemistry
Bioengineering
010501 environmental sciences
01 natural sciences
[CHIM.GENI]Chemical Sciences/Chemical engineering
Mass concentration (chemistry)
Geometric standard deviation
General Materials Science
[PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]
[SPI.NANO]Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronics
0105 earth and related environmental sciences
010405 organic chemistry
Ranging
General Chemistry
Condensed Matter Physics
Atomic and Molecular Physics
and Optics
0104 chemical sciences
Aerosol
Modeling and Simulation
Log-normal distribution
Lung-deposited surface area concentration
Particle
Particle size
Count median diameter
Biological system
Zdroj: Journal of Nanoparticle Research
Journal of Nanoparticle Research, Springer Verlag, 2013, 15, pp.2104. ⟨10.1007/s11051-013-2104-5⟩
Journal of Nanoparticle Research, Springer Verlag, 2014, 15, ⟨10.1007/s11051-013-2104-5⟩
ISSN: 1388-0764
1572-896X
Popis: International audience; Due to the increasing use of nanomaterials in research and product development, it is probable that the number of situations of occupational exposure to them is also rising. The same is true for the number of workers. Although current research in nanotoxicology is far from conclusive, it is clear that relying on mass concentration and chemical composition alone is not appropriate in all cases and alternative measurement methods and approaches need to be developed. In this work, we propose a method based on simultaneous size-integrated measurements of two particle concentrations (number and lung-deposited surface area, CNC/NSAM), and on the estimation of the average size of potentially inhaled particles from the combination of these measurements. The proposed method could be part of a measurement strategy that is practical as it would use field-portable, commercially available aerosol instruments. In the absence of instruments providing real-time size-resolved measurements, this original approach can be carried out as considering that the ratio of these concentrations is a monotonous function of particle size. Indeed, the latter function depends only on the geometric standard deviation of airborne particle number size distribution, assumed to be lognormal. Compared to SMPS data for polydisperse aerosols having three chemical natures with count median diameters ranging from 64 to 177 nm, experimental results were obtained with acceptable relative discrepancies of ±30 %. Though the method proposed is less accurate than traditional instruments like SMPS, it can be used for workplace air monitoring or as a screening tool to detect the presence of airborne nanoparticles
Databáze: OpenAIRE
Externí odkaz: