Pathophysiological and molecular considerations of viral and bacterial infections during maternal-fetal and –neonatal interactions of SARS-CoV-2, Zika, and Mycoplasma infectious diseases

Autor: Fernanda Blasina, Marianela Rodríguez Rey, Rosana Sapiro, Gabriel Anesetti, Luisina Chavarría, Romina Cardozo, Gonzalo Ferreira, Garth L. Nicolson, Grazzia Rey, Luis Sobrevia
Přispěvatelé: Universidad de la Republica, Pontificia Universidad Católica de Chile, Universidad de Sevilla, Universidade Estadual Paulista (UNESP), University of Queensland, University Medical Center Groningen, The Institute for Molecular Medicine, Universidad de Sevilla. Departamento de Fisiología
Jazyk: angličtina
Rok vydání: 2021
Předmět:
CHRONIC KIDNEY-DISEASE
Microcephaly
Placenta
Disease
medicine.disease_cause
AMNIOTIC-FLUID
ZIKV
Zika virus
CoVs
coronaviruses
CSF
cerebrospinal fluid
TNF-α
tumor necrosis factor-α
Zika virus
law.invention
FRC
functional residual capacity
Mycoplasma
law
Pregnancy
S
spike protein
Epidemiology
ILs
interleukins
DIC
disseminated intravascular coagulation
RAS
renin–angiotensin–aldosterone system
Pregnancy Complications
Infectious
HSV
Herpes simplex virus
Maternal-Fetal Exchange
VERTICAL TRANSMISSION
COVID-19
coronavirus disease 2019
biology
Zika Virus Infection
UREAPLASMA-UREALYTICUM
NF-κB
nuclear factor kappa-light-chain-enhancer of activated B cells
PRMBL
premature rupture of membranes before labor
CS
cytokine storm
Intensive care unit
HIV
human immunodeficiency virus
Breast Feeding
Viruses
Host-Pathogen Interactions
Molecular Medicine
Female
Disease Susceptibility
BV
bacterial vaginitis
TORCH
toxoplasmosis
rubella
cytomegalovirus and Herpes virus-like infections
ACE2
angiotensin-converting enzyme 2 receptors
medicine.medical_specialty
MIPL
medically induced premature labor
MAS
Macrophage Activation Syndrome
VIRUS-INFECTION
Article
WHO
World Health Organization
NK
Natural Killer
WEST NILE
medicine
Humans
Mycoplasma Infections
TMPRSS2
Type II transmembrane serine protease
Molecular Biology
APTT
activated partial thromboplastin time
ARDS
acute respiratory distress syndrome
B/L7
cathepsin B/L7
Fetus
Bacteria
business.industry
AF
amniotic fluid
SARS-CoV-2
Ang 1–7
angiotensin 1–7
GFR
glomerular filtration rate
SPL
spontaneous premature labor
Infant
Newborn
CDC
Centers for Disease Control and Prevention
USA
Neonates
COVID-19
Maternal-fetal interphase
CMV
cytomegalovirus
Zika Virus
biology.organism_classification
medicine.disease
AT1R
angiotensine type 1 receptor
Infectious Disease Transmission
Vertical
NGS
next-generation sequencing
MasR
Mas Receptor (for angiotensin 1–7)
RESPIRATORY PHYSIOLOGY
SVR
systemic vascular resistance
Immunology
business
TO-CHILD TRANSMISSION
Biomarkers
Zdroj: Biochimica et Biophysica Acta. Molecular Basis of Disease
Biochimica et biophysica acta-Molecular basis of disease, 1868(1):166285. ELSEVIER SCIENCE BV
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
ISSN: 1879-260X
0925-4439
Popis: Made available in DSpace on 2022-04-28T19:45:52Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-01-01 Agencia Nacional de Investigación e Innovación Comisión Sectorial de Investigación Científica Rijksuniversiteit Groningen Universidad de la República Uruguay Fondo Nacional de Desarrollo Científico y Tecnológico During pregnancy, a series of physiological changes are determined at the molecular, cellular and macroscopic level that make the mother and fetus more susceptible to certain viral and bacterial infections, especially the infections in this and the companion review. Particular situations increase susceptibility to infection in neonates. The enhanced susceptibility to certain infections increases the risk of developing particular diseases that can progress to become morbidly severe. For example, during the current pandemic caused by the SARS-CoV-2 virus, epidemiological studies have established that pregnant women with COVID-19 disease are more likely to be hospitalized. However, the risk for intensive care unit admission and mechanical ventilation is not increased compared with nonpregnant women. Although much remains unknown with this particular infection, the elevated risk of progression during pregnancy towards more severe manifestations of COVID-19 disease is not associated with an increased risk of death. In addition, the epidemiological data available in neonates suggest that their risk of acquiring COVID-19 is low compared with infants (
Databáze: OpenAIRE
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