Clean and Efficient Iodination of Thiophene Derivatives
| Autor: | Jérémie Grolleau, Pierre Frère, Frédéric Gohier |
|---|---|
| Přispěvatelé: | MOLTECH-Anjou, Université d'Angers (UA)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS) |
| Rok vydání: | 2015 |
| Předmět: |
thiophene
Ethanol 010405 organic chemistry Chemistry Organic Chemistry 4-toluenesulfonic acid Halogenation Regioselectivity 010402 general chemistry 01 natural sciences Thiophene derivatives Catalysis 0104 chemical sciences green methodology chemistry.chemical_compound regioselectivity odination Thiophene [CHIM]Chemical Sciences Organic chemistry |
| Zdroj: | SYNTHESIS SYNTHESIS, Georg Thieme Verlag, 2015, 24 (47), pp.3901-3906. ⟨10.1055/s-0035-1560480⟩ |
| ISSN: | 1437-210X 0039-7881 |
| DOI: | 10.1055/s-0035-1560480 |
| Popis: | International audience; Iodination of thiophene derivatives is realized using a simple, fast, and efficient methodology. Iodination of thiophene and 2- or 3-substituted or 3,4-disubstituted thiophenes with N-iodosuccinimide (NIS) activated with 4-toluenesulfonic acid in ethanol gives pure iodinated products that require no further purification. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|