Insights Into Epiretinal Membranes: Presence of Ectopic Inner Foveal Layers and a New Optical Coherence Tomography Staging Scheme
| Autor: | Andrea Govetto, Robert A. Lalane, David Sarraf, Marta S. Figueroa, Jean Pierre Hubschman |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male Fovea Centralis medicine.medical_specialty Time Factors Visual acuity genetic structures Fundus Oculi Visual Acuity Severity of Illness Index 03 medical and health sciences 0302 clinical medicine Optical coherence tomography Foveal Ophthalmology medicine Humans Fluorescein Angiography Outer nuclear layer Aged Retrospective Studies Aged 80 and over Retina medicine.diagnostic_test business.industry Fovea centralis Epiretinal Membrane Anatomy Middle Aged Fluorescein angiography medicine.disease eye diseases medicine.anatomical_structure 030221 ophthalmology & optometry Female sense organs Epiretinal membrane medicine.symptom business Tomography Optical Coherence 030217 neurology & neurosurgery Follow-Up Studies |
| Zdroj: | American Journal of Ophthalmology. 175:99-113 |
| ISSN: | 0002-9394 |
| Popis: | Purpose To describe the presence of continuous ectopic inner foveal layers associated with epiretinal membranes (ERMs) and to present a new optical coherence tomography (OCT) staging system of ERMs. Design Retrospective multicenter observational case series. Methods Clinical charts and spectral-domain OCT images of 194 eyes of 172 consecutive patients diagnosed with ERMs were reviewed and analyzed. Results The presence of continuous ectopic inner foveal layers was identified in 63 out of 194 eyes (32.5%) and this morphology was significantly associated with lower visual acuity. ERMs were divided into 4 stages. Stage 1 (43 out of 194 eyes, 22.1%) ERMs were mild and thin and a foveal depression was present. Stage 2 (88 out of 194 eyes, 45.4%) ERMs were associated with widening of the outer nuclear layer and loss of the foveal depression. Stage 3 (51 out of 194 eyes, 26.3%) ERMs were associated with continuous ectopic inner foveal layers crossing the entire foveal area. In stages 1, 2, and 3 all retinal layers were clearly defined on OCT. Stage 4 ERMs (12 out of 194 eyes, 6.2%) were thick and associated with continuous ectopic inner foveal layers. In addition, retinal layers were disrupted. Visual acuity progressively declined from stage 1 through stage 4 ( P Conclusions The presence of continuous ectopic inner foveal layers in ERMs is a newly described OCT finding associated with significant vision loss and is an essential element of a novel OCT-based grading scheme of ERMs that may influence visual prognosis. |
| Databáze: | OpenAIRE |
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