The Enigmatic Origin of Bovine mtDNA Haplogroup R: Sporadic Interbreeding or an Independent Event of Bos primigenius Domestication in Italy?

Autor: Silvia Bonfiglio, Paolo Ajmone-Marsan, Luigi Liotta, Anna Olivieri, Antonio Torroni, Luca Ferretti, Licia Colli, Alessandro Achilli, Riccardo Negrini
Předmět:
Evolutionary Genetics
bovine mtDNA
Animal Evolution
ved/biology.organism_classification_rank.species
lcsh:Medicine
Animal Phylogenetics
Polymerase Chain Reaction
Haplogroup
Cattle domestication
lcsh:Science
Phylogeny
Genetics
Likelihood Functions
Multidisciplinary
Ecology
Settore AGR/17 - ZOOTECNICA GENERALE E MIGLIORAMENTO GENETICO
Phylogenetic tree
mtDNA
Ruminants
humanities
Phylogenetics
Mammalogy
Italy
Biogeography
Animals
Domestic
Research Article
Gene Flow
Mitochondrial DNA
Animal Types
Agro-Population Ecology
Large Animals
Biology
DNA
Mitochondrial
Evolution
Molecular
Animals
Evolutionary Systematics
Domestication
Crosses
Genetic
Evolutionary Biology
Models
Genetic
ved/biology
Taurine cattle
lcsh:R
Haplotype
Genetic Variation
Paleontology
Aurochs
biology.organism_classification
Organismal Evolution
Haplotypes
Genome
Mitochondrial
Genetic Polymorphism
lcsh:Q
Cattle
Veterinary Science
Animal Genetics
Zoology
Agroecology
Population Genetics
Human mitochondrial DNA haplogroup
Zdroj: Università Cattolica del Sacro Cuore-IRIS
PLoS ONE
PLoS ONE, Vol 5, Iss 12, p e15760 (2010)
Popis: Background When domestic taurine cattle diffused from the Fertile Crescent, local wild aurochsen (Bos primigenius) were still numerous. Moreover, aurochsen and introduced cattle often coexisted for millennia, thus providing potential conditions not only for spontaneous interbreeding, but also for pastoralists to create secondary domestication centers involving local aurochs populations. Recent mitochondrial genomes analyses revealed that not all modern taurine mtDNAs belong to the shallow macro-haplogroup T of Near Eastern origin, as demonstrated by the detection of three branches (P, Q and R) radiating prior to the T node in the bovine phylogeny. These uncommon haplogroups represent excellent tools to evaluate if sporadic interbreeding or even additional events of cattle domestication occurred. Methodology The survey of the mitochondrial DNA (mtDNA) control-region variation of 1,747 bovine samples (1,128 new and 619 from previous studies) belonging to 37 European breeds allowed the identification of 16 novel non-T mtDNAs, which after complete genome sequencing were confirmed as members of haplogroups Q and R. These mtDNAs were then integrated in a phylogenetic tree encompassing all available P, Q and R complete mtDNA sequences. Conclusions Phylogenetic analyses of 28 mitochondrial genomes belonging to haplogroups P (N = 2), Q (N = 16) and R (N = 10) together with an extensive survey of all previously published mtDNA datasets revealed major similarities between haplogroups Q and T. Therefore, Q most likely represents an additional minor lineage domesticated in the Near East together with the founders of the T subhaplogroups. Whereas, haplogroup R is found, at least for the moment, only in Italy and nowhere else, either in modern or ancient samples, thus supporting an origin from European aurochsen. Haplogroup R could have been acquired through sporadic interbreeding of wild and domestic animals, but our data do not rule out the possibility of a local and secondary event of B. primigenius domestication in Italy.
Databáze: OpenAIRE
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