Plant arginyltransferases (ATEs)
| Autor: | Maite F S Vaslin, Tatiane da Franca Silva, Anna Karoline Silva Fausto, Elisson Romanel, Tatiana Domitrovic |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Arginine lcsh:QH426-470 Plant Molecular Biology N-end rule plant Biology Protein degradation 03 medical and health sciences Genetics Transferase Molecular Biology Peptide sequence chemistry.chemical_classification food and beverages ATE argyniltransferase lcsh:Genetics 030104 developmental biology Enzyme chemistry Proteasome Biochemistry protein degradation Function (biology) |
| Zdroj: | Genetics and Molecular Biology, Volume: 40, Issue: 1 Supplement 1, Pages: 253-260, Published: 13 FEB 2017 Genetics and Molecular Biology v.40 n.1 suppl.1 2017 Genetics and Molecular Biology Sociedade Brasileira de Genética (SBG) instacron:SBG Genetics and Molecular Biology, Iss 0 |
| Popis: | Regulation of protein stability and/or degradation of misfolded and damaged proteins are essential cellular processes. A part of this regulation is mediated by the so-called N-end rule proteolytic pathway, which, in concert with the ubiquitin proteasome system (UPS), drives protein degradation depending on the N-terminal amino acid sequence. One important enzyme involved in this process is arginyl-t-RNA transferase, known as ATE. This enzyme acts post-translationally by introducing an arginine residue at the N-terminus of specific protein targets to signal degradation via the UPS. However, the function of ATEs has only recently begun to be revealed. Nonetheless, the few studies to date investigating ATE activity in plants points to the great importance of the ATE/N-end rule pathway in regulating plant signaling. Plant development, seed germination, leaf morphology and responses to gas signaling in plants are among the processes affected by the ATE/N-end rule pathway. In this review, we present some of the known biological functions of plant ATE proteins, highlighting the need for more in-depth studies on this intriguing pathway. |
| Databáze: | OpenAIRE |
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