The diagnostic accuracy of fine-needle cytology of Hurthle cell lesions; A comprehensive cytological, clinical and ultrasonographic experience
| Autor: | Pio Zeppa, Gaetano De Rosa, Vincenzo Giuseppe Di Crescenzo, Alessia Caleo, Alessandro Vatrella, Luigi Landolfi, Mario Vitale, Anna Lucia Peluso |
|---|---|
| Přispěvatelé: | Caleo, Alessia, Landolfi, Luigi, Vitale, Mario, Di Crescenzo, Vincenzo, Vatrella, Alessandro, DE ROSA, Gaetano, Peluso, Anna Lucia, Zeppa, Pio |
| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty Pathology Goiter endocrine system diseases Adolescent Bethesda system Biopsy Fine-Needle 030209 endocrinology & metabolism Diagnostic accuracy Hashimoto Disease Hurthle Cells Thyroid carcinoma 03 medical and health sciences Young Adult Hurthle cell 0302 clinical medicine Hashimoto thyroiditis Cytology Ultrasound Medicine Adenoma Oxyphilic Humans Thyroid Neoplasms Thyroid Nodule Hurthle cells Aged Ultrasonography Hyperplasia medicine.diagnostic_test business.industry Rapid on-site evaluation General Medicine Middle Aged medicine.disease Fine needle cytology Carcinoma Papillary 030220 oncology & carcinogenesis Surgery Radiology business Goiter Nodular |
| Zdroj: | International journal of surgery (London, England). 28 |
| ISSN: | 1743-9159 |
| Popis: | Background Fine-needle cytology (FNC) diagnosis and pre-operative classification of Hurthle cells (HC) lesions may be difficult. Rapid on-site evaluation (ROSE) enhances the efficiency of FNC, mainly when utilized in close combination to clinical and ultrasound (US) data. Objective to describe an experience on HC FNC with contextual clinical,US and ROSE evaluation and assess if this comprehensive approach improves the FNC accuracy of HC lesions. Methods FNC of 112 HC lesion were diagnosed and classified, according to the Bethesda system, by clinical, US and ROSE in one year. All the cases were controlled by follow-up and histology when performed. Results Eighty-five cases were diagnosed HC rich goiter or Hashimoto thyroiditis and were classified THY2; 5 cases were diagnosed hyperplastic nodular goiter and classified THY3A. Eight cases were diagnosed suspect neoplasia and classified THY3B. Two cases were diagnosed suspect HC papillary thyroid carcinoma (PTC) and classified THY4 and 2 cases were diagnosed HC-PTC and classified THY5. THY3B, THY4, THY5 and 1 THY3A were histologically controlled. FNC were confirmed in 14 out of the 17 THY3-THY5 cases. Conclusions A comprehensive diagnostic approach that include FNC, clinical data, US and ROSE improves the diagnosis and classification of HC lesions. |
| Databáze: | OpenAIRE |
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