Myc in model organisms: A view from the flyroom
Autor: | Laura A. Johnston, Claire de la Cova |
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Rok vydání: | 2006 |
Předmět: |
Cancer Research
Cell division ved/biology.organism_classification_rank.species Cell Ribosome biogenesis Article Animals Genetically Modified Proto-Oncogene Proteins c-myc medicine Animals Drosophila Proteins Model organism Drosophila Genetics biology ved/biology fungi Gene Expression Regulation Developmental biology.organism_classification Drosophila melanogaster medicine.anatomical_structure Trans-Activators Drosophila Protein Signal Transduction |
Zdroj: | Seminars in Cancer Biology. 16:303-312 |
ISSN: | 1044-579X |
Popis: | The Myc transcription factor regulates fundamental processes in a cell's life: its growth, division, and survival. Myc is conserved throughout metazoan phyla, and its identification in the fruit fly, Drosophila melanogaster has led to new insights in Myc's physiological roles. In this review, we describe recent research on the biology of Myc and its family members in Drosophila, paying particular attention to its role in the control of growth during development. |
Databáze: | OpenAIRE |
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