Mixed-function oxidase studies in the redfish, sciaenops ocellata, from galveston bay, texas
| Autor: | Cynthia Hung Stahl, Carl S. Hacker, Lester G. Sultatos, Sheldon D. Murphy |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Aroclors
Redfish Immunology In Vitro Techniques Biology Mixed Function Oxygenases Nitrophenols Mice chemistry.chemical_compound Nitrophenol Species Specificity Animals Biotransformation Pharmacology chemistry.chemical_classification Oxidase test Parathion Fishes Temperature Metabolism Chlorodiphenyl (54% Chlorine) Hydrogen-Ion Concentration biology.organism_classification Texas Molecular biology Mixed Function Oxidase Enzyme chemistry Biochemistry Enzyme Induction Microsomes Liver Microsome |
| Zdroj: | Comparative Biochemistry and Physiology Part C: Comparative Pharmacology. 79:177-182 |
| ISSN: | 0306-4492 |
| DOI: | 10.1016/0742-8413(84)90182-8 |
| Popis: | 1. The metabolism of parathion to para -nitrophenol (PNP) in redfish ( Sciaenops ocellata ) liver microsomes has been both identified and characterized. 2. This mixed-function oxidase (MFO) reaction in redfish requires NADPH and is inhibited by carbon monoxide. It exhibits a temperature optimum of 25°C but no clear pH optimum between 7.0–8.5. 3. Redfish hepatic microsomal MFOs were not induced by 2.5 days after a single i.p. injection of 88 mg Aroclor 1254/kg body wt, but under the same dosage and time conditions male albino Swiss mice were significantly induced ( p |
| Databáze: | OpenAIRE |
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