| Autor: |
Yuningsih, Dyah Woro Kartiko Kusumo Wardani, Mulyohadi Ali, Husnul Khotimah, Nurdiana, Wibi Riawan, Dianita Primihastuti, Fitra Arsy Nur Cory'ah, Ariati, Linda Ika Puspita, Primaditya, Vanda, Zakiah |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| DOI: |
10.5281/zenodo.6848812 |
| Popis: |
Stunting is known as length for age below minus two standard deviations (Centella asiaticais a high antioxidant herbal plant with anti-inflammatory properties. This study aimed to investigate the effect ofCentella asiaticaethanolic extract on the rotenone-induced stunting zebrafish (Danio rerio) larvae model through GLUT 1 and osteocalcin expressions. This study found that 12.5 ppb of rotenone can induce about 6 dpf (day post-fertilization) zebrafish larvae into stunting. The effect ofCentella asiaticaethanolic extract on increasing body length in stunting zebrafish larvae works by increasing the expression of GLUT 1 and osteocalcin expressions. The correlation test showed a positive and strong relationship between this ethanolic extract level with GLUT 1 and Osteocalcin expression. Thus, theCentella asiaticaethanolic extract effectively promotes the body length by elevating the expression of GLUT 1 and osteocalcin in stunting zebrafish larvae. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
