Myocardial blood flows and reserves on solid state camera: Correlations with coronary history and cardiovascular risk factors
Autor: | Jean-Baptiste Pinaquy, Adel Mamou, Paul Ferenczi, Pierre Coste, Laurence Bordenave, Yassine Mamou, Q. Ceyrat, Thierry Couffinhal |
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Rok vydání: | 2021 |
Předmět: |
medicine.medical_specialty
Population Cardiovascular risk factors Solid-state Coronary Artery Disease 030204 cardiovascular system & hematology 030218 nuclear medicine & medical imaging Coronary artery disease 03 medical and health sciences Myocardial perfusion imaging 0302 clinical medicine Risk Factors Coronary Circulation Internal medicine Diabetes mellitus medicine Humans Radiology Nuclear Medicine and imaging Risk factor education education.field_of_study medicine.diagnostic_test business.industry Myocardial Perfusion Imaging Blood flow medicine.disease Cardiovascular Diseases Heart Disease Risk Factors Positron-Emission Tomography Cardiology Cardiology and Cardiovascular Medicine business |
Zdroj: | Journal of Nuclear Cardiology. 29:1671-1678 |
ISSN: | 1532-6551 1071-3581 |
Popis: | Study designed to test association between stress-induced myocardial blood flow (sMBF), resting MBF (rMBF), and MBF reserve (MFR) and coronary artery disease (CAD) in a population of CAD and non-coronary patients. Secondary objectives were to confront visual analysis and dynamic analysis and to explore potential association between MBF and several cardiovascular risk factors METHODS: A total of 155 patients who underwent dynamic myocardial perfusion imaging on a CZT camera were included. sMBF, rMBF, and MFR were evaluated, and cardiovascular risk was assessed.Significantly lower total sMBF and MFR were observed in CAD patient vs non-CAD patient. In comparison with visual analysis, lower sMBF were found in pathologic territory, lower rMBF in necrotic territory and lower MFR in necrotic ones. A significant correlation between total sMBF, rMBF and diabetes was found.sMBF and MFR as assessed on CZT gamma-cameras can be used to determine the coronary state. Low total sMBF might be an independent risk factor of coronaropathy. An inverse correlation was suggested between total sMBF and rMBF with diabetes. |
Databáze: | OpenAIRE |
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