Neutrophil-to-lymphocyte ratio as a predictive marker of metabolic syndrome
| Autor: | Lo-Yip Yu, Shou-Chuan Shih, Wan-Shan Liu, Hung-Ju Ko, Kuang-Chun Hu, Chung-Lieh Hung, Chuan-Chuan Liu |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty Neutrophils Observational Study Risk Assessment Gastroenterology 03 medical and health sciences 0302 clinical medicine Predictive Value of Tests Risk Factors Internal medicine medicine Humans Lymphocyte Count Lymphocytes 030212 general & internal medicine metabolic syndrome (MS) Neutrophil to lymphocyte ratio Stage (cooking) National Cholesterol Education Program neutrophil-to-lymphocyte ratio (NLR) Retrospective Studies Metabolic Syndrome Predictive marker Receiver operating characteristic business.industry fungi Retrospective cohort study General Medicine Middle Aged Prognosis medicine.disease ROC Curve 030220 oncology & carcinogenesis Predictive value of tests Female Metabolic syndrome business Biomarkers Research Article |
| Zdroj: | Medicine |
| ISSN: | 1536-5964 0025-7974 |
| DOI: | 10.1097/md.0000000000017537 |
| Popis: | Neutrophil-to-lymphocyte ratio (NLR) serves as a strong prognostic indicator for patients suffering from various diseases. Neutrophil activation promotes the recruitment of a number of different cell types that are involved in acute and chronic inflammation and are associated with cancer treatment outcome. Measurement of NLR, an established inflammation marker, is cost-effective, and it is likely that NLR can be used to predict the development of metabolic syndrome (MS) at an early stage. MS scores range from 1 to 5, and an elevated MS score indicates a greater risk for MS. Monitoring NLR can prevent the risk of MS. A total of 34,013 subjects were enrolled in this study. The subjects (score 0–5) within the 6 groups were classified according to the National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) criteria, and all anthropometrics, laboratory biomarkers, and hematological measurements were recorded. For the 6 groups, statistical analysis and receiver operating characteristic (ROC) curves were used to identify the development of MS. Analysis of the ROC curve indicated that NLR served as a good predictor for MS. An MS score of 1 to 2 yielded an acceptable discrimination rate, and these rates were even higher for MS scores of 3 to 5 (P |
| Databáze: | OpenAIRE |
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