Anticonvulsant-induced dyskinesia
| Autor: | Megdad Zaatreh |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Dyskinesia
Drug-Induced Movement disorders Side effect business.industry medicine.medical_treatment Dopaminergic General Medicine Paroxysmal dyskinesia Bioinformatics medicine.disease Epilepsy Anticonvulsant Dyskinesia Risk Factors Anesthesia otorhinolaryngologic diseases medicine Humans Anticonvulsants Pharmacology (medical) medicine.symptom business Adverse effect |
| Zdroj: | Expert Opinion on Drug Safety. 2:385-393 |
| ISSN: | 1744-764X 1474-0338 |
| DOI: | 10.1517/14740338.2.4.385 |
| Popis: | Anticonvulsant-induced dyskinesia (AID) is an underdiagnosed side effect of many anticonvulsants that may take place during initial or chronic treatment at normal or toxic drug levels. The occurrence of AID subjects the patient to another medical condition and may prompt an extensive work-up. Similarities with other drug-induced dyskinesias and some animal studies suggest that dopaminergic dysfunction in the basal ganglia is pivotal in the occurrence of dyskinesia. Clinical presentation and outcomes are variable; however, in most cases, dyskinesias respond well to anticonvulsant withdrawal. Enhancing the awareness of AID is important in light of the recent development of many new anticonvulsants and their wider clinical use. |
| Databáze: | OpenAIRE |
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