Parylene Photonics: A Flexible, Broadband Optical Waveguide Platform with Integrated Micromirrors for Biointerfaces
| Autor: | Jay W. Reddy, Maysamreza Chamanzar, Maya Lassiter |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Biocompatible polymers
Materials science Materials Science (miscellaneous) FOS: Physical sciences 02 engineering and technology Applied Physics (physics.app-ph) lcsh:Technology Industrial and Manufacturing Engineering 03 medical and health sciences chemistry.chemical_compound Parylene Broadband Nanobiotechnology Electrical and Electronic Engineering 030304 developmental biology 0303 health sciences Polydimethylsiloxane lcsh:T business.industry Physics - Applied Physics 021001 nanoscience & nanotechnology Condensed Matter Physics Biocompatible material Atomic and Molecular Physics and Optics chemistry lcsh:TA1-2040 Optoelectronics Photonics lcsh:Engineering (General). Civil engineering (General) 0210 nano-technology business Biological imaging |
| Zdroj: | Microsystems & Nanoengineering, Vol 6, Iss 1, Pp 1-14 (2020) |
| Popis: | Targeted light delivery into biological tissue is needed in applications such as optogenetic stimulation of the brain and in vivo functional or structural imaging of tissue. These applications require very compact, soft, and flexible implants that minimize damage to tissue. Here, we demonstrate a novel implantable photonic platform based on a high-density, flexible array of ultracompact (30 ${\mu}$m x 5 ${\mu}$m), low-loss (3.2 dB/cm at ${\lambda}$ = 680 nm, 4.1 dB/cm at ${\lambda}$ = 633 nm, 4.9 dB/cm at ${\lambda}$ = 532 nm, 6.1 dB/cm at ${\lambda}$ = 450 nm) optical waveguides made of biocompatible polymers Parylene C and polydimethylsiloxane (PDMS). This photonic platform features unique embedded input/output micro-mirrors that redirect light from the waveguides perpendicularly to the surface of the array for localized, patterned illumination in tissue. This architecture enables the design of a fully flexible, compact integrated photonic system for applications such as in vivo chronic optogenetic stimulation of brain activity. Comment: 20 pages, 7 figures, submitted to Nature Microsystems and Nanoengineering |
| Databáze: | OpenAIRE |
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