Early introductions and transmission of SARS-CoV-2 variant B.1.1.7 in the United States
| Autor: | Christopher E. Mason, A. Craney, Lars F. Westblade, Anthony Muyombwe, Alexis Russell, Jafar Razeq, Chen Liu, Matthew Shudt, Jonathan Plitnick, Mary E. Petrone, Peter W. Cook, Anne E. Watkins, Jianhui Wang, Ardath Grills, Erasmus Schneider, Chaney C. Kalinich, Lin Cong, Nathan D. Grubaugh, Jessica E. Rothman, Pei Hui, Chantal B.F. Vogels, Caleb Neal, Priya Velu, Matthew MacKay, Anderson F. Brito, Tara Alpert, Kirsten St. George, Mallery I. Breban, Nike Beaubier, John P. Kelly, Marie L. Landry, Duncan MacCannell, Gaurav Khullar, Megan Nash, William J. Fitzsimmons, David R. Peaper, Stephanie Morrison, Andrew L Valesano, Randy Downing, Simon Dellicour, Melissa M. Cushing, Joel T. Dudley, Hanna Rennert, Joseph R. Fauver, Steven Murphy, Erica Lasek-Nesselquist, Stephen M. Bart, Jessica Metti, Eva Laszlo, Adam S. Lauring |
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| Rok vydání: | 2021 |
| Předmět: |
0303 health sciences
2019-20 coronavirus outbreak medicine.medical_specialty Lineage (genetic) Coronavirus disease 2019 (COVID-19) Transmission (medicine) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Public health Biology Article General Biochemistry Genetics and Molecular Biology 03 medical and health sciences 0302 clinical medicine Epidemiology medicine Diagnostic data 030217 neurology & neurosurgery 030304 developmental biology Demography |
| Zdroj: | Cell |
| ISSN: | 0092-8674 |
| DOI: | 10.1016/j.cell.2021.03.061 |
| Popis: | The emergence and spread of SARS-CoV-2 lineage B.1.1.7, first detected in the United Kingdom, has become a global public health concern because of its increased transmissibility. Over 2500 COVID-19 cases associated with this variant have been detected in the US since December 2020, but the extent of establishment is relatively unknown. Using travel, genomic, and diagnostic data, we highlight that the primary ports of entry for B.1.1.7 in the US were in New York, California, and Florida. Furthermore, we found evidence for many independent B.1.1.7 establishments starting in early December 2020, followed by interstate spread by the end of the month. Finally, we project that B.1.1.7 will be the dominant lineage in many states by mid to late March. Thus, genomic surveillance for B.1.1.7 and other variants urgently needs to be enhanced to better inform the public health response. The SARS-CoV-2 variant B.1.1.7 was introduced to the United States in early December 2020 and soon became established within many communities. The primary points of entry into the US are identified as NY, CA, and FL, and exponential growth in these states resulted in spread to neighboring states. |
| Databáze: | OpenAIRE |
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