Increased incidences of noninfectious comorbidities among aging populations living with human immunodeficiency virus in Ecuador: a multicenter retrospective analysis
| Autor: | Nelson Cevallos, Andres Izurieta, Isabel Hernández, Enrique Teran, Julio Barzallo, Gabriela Yerovi, Rita Vera, Santiago Terán, Simón Beltrán, Alberto Castillo, Patricio Hernández, Camilo López, Alejandra Mendoza |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
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medicine.medical_specialty Epidemiology HIV combined antiretroviral therapy Population HIV diagnosis Dermatology HIV in developing countries HIV in Ecuador 030312 virology Overweight HIV/AIDS - Research and Palliative Care 03 medical and health sciences 0302 clinical medicine Virology Internal medicine medicine HIV treatment 030212 general & internal medicine people living with HIV education Depression (differential diagnoses) Original Research 0303 health sciences education.field_of_study HIV noninfectious comorbidities business.industry Health Policy Public health medicine.disease Obesity Regimen Infectious Diseases medicine.symptom business Dyslipidemia |
| Zdroj: | HIV/AIDS (Auckland, N.Z.) |
| ISSN: | 1179-1373 |
| Popis: | Isabel Hernández,1,2 Julio Barzallo,3 Simón Beltrán,4 Alberto Castillo,5 Nelson Cevallos,6 Patricio Hernández,7 Camilo López,8 Rita Vera,9 Gabriela Yerovi,10 Alejandra Mendoza,1 Santiago Terán,1 Andres Izurieta,11 Enrique Teran11Colegio de Ciencias de la Salud, Universidad San Francisco de Quito, Quito, Ecuador; 2Facultad de Enfermería, Pontificia Universidad Católica del Ecuador, Quito, Ecuador; 3Hospital Teofilo Dávila, Ministerio de Salud Pública, Machala, Ecuador; 4Hospital Carlos Andrade Marín, Instituto Ecuatoriano de Seguridad Social, Quito, Ecuador; 5Hospital Eugenio Espejo, Ministerio de Salud Pública, Quito, Ecuador; 6Hospital Enrique Garcés, Ministerio de Salud Pública, Quito, Ecuador; 7Hospital de Infectología Dr. José Daniel Rodríguez Maridueña, Ministerio de Salud Pública, Guayaquil, Ecuador; 8Hospital Teodoro Maldonado Carbo, Instituto Ecuatoriano de Seguridad Social, Guayaquil, Ecuador; 9Hospital Abel Gilbert Pontón, Ministerio de Salud Pública, Guayaquil, Ecuador; 10Programa Nacional para Control del VIH, Ministerio de Salud Pública, Quito, Ecuador; 11Department of Computer Engineering, College of Engineering, University of South Florida, Tampa, FL, USAIntroduction: Besides the well-known increased risk of developing HIV-related infectious comorbidities; compared with the general population, people living with HIV (PLHIV) may also have an increased risk of developing noninfectious comorbidities (NICMs). This is the first study intended to determine the NICMs rates affecting PLHIV who were under cART regimen in Ecuador.Methods: A total of 503 HIV-positive patients were evaluated during the period June 2015-November 2016 and included in a multicenter retrospective, cross-sectional study conducted in seven main government and nongovernment community-based hospitals in Ecuador.Results: The average age of the participants was 39.2±11.9 years old and the majority of them were male (67.2%). The average age at HIV diagnosis was 34.1 years old and cART in average was started 15.9 months after HIV-diagnosis. Recruited patients were receiving cART for an average of 59.2±40.2 months. Only 9.9% (n=50) of the patients did not show any NICMs. Diabetes and pre-diabetes was found in 6% (n=30) and 16.3% (n=82) patients, respectively; however, dyslipidemia and overweight/obesity was frequent, as they affected 41.4% (n=208) and 36.4% (n=183) patients, respectively. Sixty patients (11.9%) were diagnosed with depression and 28.2% (n=142) of the studied subjects were found to have other NICMs.Conclusion: Prevalence of NICMs among subjects under cART was greater than that reported among the Ecuadorian general population, therefore specific public health actions are required to make patients aware of and prevent NICMs among PLHIV in Ecuador.Keywords: HIV noninfectious comorbidities, people living with HIV, HIV combined antiretroviral therapy, HIV diagnosis, HIV treatment, HIV in developing countries, HIV in Ecuador |
| Databáze: | OpenAIRE |
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