Exploring an anomaly: the synthesis of 7,7'-diazaindirubin through a 7-azaindoxyl intermediate
| Autor: | James A. Shriver, Andrew C. Patterson, James R. DeYoung, Katelyn R. Wang, Richard J. Lipsius |
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| Rok vydání: | 2020 |
| Předmět: |
0303 health sciences
010405 organic chemistry General Chemical Engineering Condensation General Chemistry 01 natural sciences Indigo 0104 chemical sciences 03 medical and health sciences chemistry.chemical_compound chemistry Computational chemistry Indoxyl Reactivity (chemistry) Anomaly (physics) 030304 developmental biology |
| Zdroj: | RSC advances. 10(60) |
| ISSN: | 2046-2069 |
| Popis: | Two independent methods generating 7-azaindoxyl as an intermediate verify that 7,7′-diazaindirubin is formed exclusively over 7,7′-diazaindigo. This contrasts with long-standing knowledge related to the reactivity of indoxyl, which proceeds via a radical-initiated homodimerization process, leading to indigo. A series of experiments confirms 7-azaindoxyl as an intermediate with results suggesting a condensation pathway followed by oxidation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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