Malignant Phyllodes Tumor of the Breast: A Practice Review
| Autor: | Fabiana Baroni Alves Makdissi, Solange Moraes Sanches, Jose Claudio Casali-da-Rocha, Almir Galvão Vieira Bitencourt, Rafael Caparica Bitton, Mauricio Doi, Ângelo Bezerra de Souza Fede, Marina De Brot, Juliana Alves de Souza, Cynthia Aparecida Bueno de Toledo Osório, Guilherme Rocha Melo Gondim, Rima Jbili, Ronaldo Pereira Souza |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Oncology
medicine.medical_specialty Review Malignant phyllodes tumor Oncologic surgery 03 medical and health sciences 0302 clinical medicine Breast cancer breast cancer Internal medicine medicine Prospective cohort study Fibroepithelial neoplasms 030304 developmental biology Therapeutic strategy 0303 health sciences lcsh:R5-920 fibroepithelial neoplasm business.industry Phyllodes tumor General Medicine medicine.disease Clinical trial 030220 oncology & carcinogenesis business lcsh:Medicine (General) |
| Zdroj: | Clinics and Practice, Vol 11, Iss 30, Pp 205-215 (2021) Clinics and Practice |
| ISSN: | 2039-7283 |
| Popis: | Introduction: Phyllodes tumor (PT) of the breast, particularly malignant phyllodes tumor (mPT), is a rare fibroepithelial neoplasm. A complex diagnosis is based on pathologic, radiologic, and clinical findings, with controversies about what is the best therapeutic strategy. Objective: Our objective was to provide an overview of the clinical, pathologic, and therapeutic aspects of this rare tumor. Conclusions: mPT is a rare presentation of breast cancer and a challenge in clinical practice. A multidisciplinary approach should take into account some aspects like pathogenic mutations and hereditary syndromes. Oncologic surgery is the fundamental approach, and the use of adjuvant therapies is still controversial due to the lack of clinical trials. Treatment recommendations should be individualized according to patient risk and preferences. Prospective studies are fundamental to clarifying the best treatment for these tumors. |
| Databáze: | OpenAIRE |
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