Early detection and integrated care for adolescents and young adults with severe psychotic disorders: rationales and design of the Integrated Care in Early Psychosis Study (ACCESS III)
| Autor: | Martin, Lambert, Daniel, Schöttle, Mary, Sengutta, Friederike, Ruppelt, Anja, Rohenkohl, Daniel, Luedecke, Luise Antonia, Nawara, Britta, Galling, Anne-Lena, Falk, Linus, Wittmann, Vivien, Niehaus, Gizem, Sarikaya, Ute, Handwerk, Wiebke, Rothländer, Liz, Rietschel, Charlotte, Gagern, Benjamin, Lange, Christina, Meigel-Schleiff, Dieter, Naber, Michael, Schulte-Markwort, Helmut, Krüger, Hans-Peter, Unger, Sven, Sippel, Sabine, Ott, Georg, Romer, Anne, Daubmann, Karl, Wegscheider, Christoph U, Correll, Benno G, Schimmelmann, Thomas, Bock, Jürgen, Gallinat, Anne, Karow |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Adult
Male Adolescent Delivery of Health Care Integrated Cost-Benefit Analysis Community Mental Health Services Cohort Studies Young Adult Early Diagnosis Treatment Outcome Psychotic Disorders Patient Satisfaction Early Medical Intervention Quality of Life Humans Female Prospective Studies Quality-Adjusted Life Years Child 610 Medicine & health Quality of Health Care |
| DOI: | 10.7892/boris.89986 |
| Popis: | The Integrated Care in Early Psychosis (ACCESS III) Study examined the efficacy and cost-effectiveness of a combined intervention consisting of strategies to improve early detection and quality of care (integrated care including therapeutic assertive community treatment) in adolescents and young adults in the early phase of a severe psychotic disorder from 2011 to 2014.This is a prospective, single-centre, 1-year cohort study comparing an intervention condition (early detection plus integrated care, n = 120) to the historical control condition (standard care, SC, n = 105) for adolescents and young adults aged 12-29 years suffering from a severe, early-phase psychotic disorder (i.e. within 2 years of treatment).Primary outcome is the rate of combined symptomatic (i.e. Positive and Negative Syndrome Scale (PANSS) criteria) and functional (i.e. Global Assessment of Functioning scale (GAF) ≥ 60 points criterion) remission over at least 6 months at study endpoint. Secondary outcome comprises the comparison of the reduction in the duration of untreated psychosis within the 4-year study duration between integrated care and SC, course of psychopathology, functioning, quality of life, satisfaction with care, cost and quality-adjusted life years (QALYs) in comparison to a historical control group.To the authors' knowledge, this is the first study assessing the efficacy and cost-effectiveness of a combined intervention consisting of early detection strategies and strategies to improve quality of care in both adolescents and young adults with early-phase psychosis. The results will be published in 2016. |
| Databáze: | OpenAIRE |
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