Repeat element-driven activation of proto-oncogenes in human malignancies
| Autor: | Björn Lamprecht, Stephan Mathas, Constanze Bonifer |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Proto-Oncogenes
Receptor Macrophage Colony-Stimulating Factor Endogeny Biology Models Biological Epigenesis Genetic Pathogenesis chemistry.chemical_compound Cell Line Tumor Humans Molecular Biology Epigenesis Regulation of gene expression Genetics Extra View NF-kappa B Terminal Repeat Sequences Cell Biology DNA Methylation Hodgkin Disease Gene Expression Regulation Neoplastic chemistry DNA methylation Cancer research Cytokines DNA Human cancer Developmental Biology |
| Zdroj: | Cell Cycle. 9:4276-4281 |
| ISSN: | 1551-4005 1538-4101 |
| Popis: | Recent data demonstrated that the raberrant activity of endogenous repetitive elements of the DNA in humans can drive the expression of proto-oncogenes. This article summarizes these results and gives an outlook on the impact of these findings on the pathogenesis and therapy of human cancer. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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