Sequences of papillomavirus DNA in equine sarcoids
| Autor: | P. B. Spradbrow, Karen Trenfield, B. A. Vanselow |
|---|---|
| Rok vydání: | 1985 |
| Předmět: |
Electrophoresis
Sarcoidosis viruses chemistry.chemical_compound stomatognathic system hemic and lymphatic diseases Animals Horses Papillomaviridae Cells Cultured Bovine papillomavirus Equine sarcoids Base Sequence biology Nucleic Acid Hybridization General Medicine biochemical phenomena metabolism and nutrition biology.organism_classification Virology Molecular biology stomatognathic diseases Restriction enzyme chemistry Cell culture DNA Viral Horse Diseases DNA |
| Zdroj: | Equine Veterinary Journal. 17:449-452 |
| ISSN: | 2042-3306 0425-1644 |
| DOI: | 10.1111/j.2042-3306.1985.tb02553.x |
| Popis: | DNA was extracted from 14 equine sarcoids, electrophoresed and hybridised with a radioactively labelled probe of bovine papillomavirus type I (BPV 1) DNA under conditions of low stringency. Twelve sarcoids contained sequences of DNA that hybridised with the probe and that comigrated with BPV 2 DNA. The viral DNAs in four of these sarcoids differed from BPV 1 and BPV 2 DNA on restriction endonuclease analysis. One of four cell lines derived from sarcoids also contained BPV 1 related DNA. The results confirm the frequent presence in equine sarcoids of unintegrated papillomaviral DNA and suggest a role for papillomavirus infection in this disease. |
| Databáze: | OpenAIRE |
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