Cell Cycle and Terminal Differentiation in Sinorhizobium meliloti
| Autor: | Sara Dendene, Angela Frascella, Quentin Nicoud, Tatiana Timchenko, Peter Mergaert, Benoit Alunni, Emanuele G. Biondi |
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| Přispěvatelé: | Institut de Biologie Intégrative de la Cellule (I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Laboratoire de chimie bactérienne (LCB), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Emanuele Biondi |
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Cell Cycle Regulation and Development in Alphaproteobacteria Emanuele Biondi. Cell Cycle Regulation and Development in Alphaproteobacteria, Springer International Publishing, pp.221-244, 2022, 978-3-030-90620-7. ⟨10.1007/978-3-030-90621-4_8⟩ Cell Cycle Regulation and Development in Alphaproteobacteria ISBN: 9783030906207 |
| Popis: | International audience; Sinorhizobium meliloti of the Alphaproteobacteria class has a fascinating spectrum of lifestyles, thriving as a free-living soil saprophyte, as an endophyte and as a nitrogen-fixing legume symbiont. In symbiosis, it undergoes a striking cellular differentiation process, which is controlled by the host plant through the activity of NCR peptides. NCRs interfere with the cell cycle of S. meliloti and transform the regular cycle consisting of strict successions of single DNA replication followed by cell division into an endoreduplication cycle of multiple genome duplications without divisions. This cellular differentiation results in giant and polyploid symbiotic bacterial cells that fix atmospheric nitrogen. Here we discuss the regulation of the free-living cell cycle in S. meliloti and present the hypothesis that the master regulator CtrA is the ultimate target of the NCR peptides, provoking the cell cycle switch in symbiosis. |
| Databáze: | OpenAIRE |
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