Efficacy of medical grade honey in the management of canine otitis externa - a pilot study
| Autor: | Emi Maruhashi, Telmo Nunes, Berta São Braz, Adriana Belas, Constança Pomba, Ana Mafalda Lourenço, José H. Duarte-correia |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Susceptibility testing Staphylococcus pseudintermedius 040301 veterinary sciences 030106 microbiology 0403 veterinary science 03 medical and health sciences Dogs Antibiotic resistance Internal medicine medicine Animals Dog Diseases High prevalence General Veterinary biology business.industry Bacterial Infections Honey 04 agricultural and veterinary sciences Otitis Externa biology.organism_classification Alternative treatment Surgery Clinical trial Otitis Mycoses medicine.symptom business |
| Zdroj: | Veterinary Dermatology. 27:93-e27 |
| ISSN: | 0959-4493 |
| DOI: | 10.1111/vde.12291 |
| Popis: | Background The high prevalence of antimicrobial resistance within otic pathogens has created a need for alternative therapies of otitis externa (OE). Evidence suggests that medical grade honey (MGH) may be effective against drug-resistant pathogens. Hypothesis/Objectives The efficacy of a commercial MGH compound was assessed in an open clinical trial. We hypothesized that it would be an effective alternative to conventional treatments. Animals Client-owned dogs (n = 15) with a confirmed diagnosis of infectious OE were enrolled in this pilot study. Methods Dogs were prescribed MGH (1 mL daily per ear) until cure was achieved or for a maximum of 21 d. Evaluation was based on weekly clinical scores, cytological progression and owner assessments of pruritus. Swab samples were submitted for culture and susceptibility testing. MGH was tested for biocidal activity against the bacterial isolates. Results Medical grade honey promoted rapid clinical progress, with 70% of dogs achieving clinical cure between days 7 and 14 and over 90% having resolved by Day 21. There was a decrease in clinical scores throughout the duration of the trial (P |
| Databáze: | OpenAIRE |
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