Granulomatosis with polyangiitis presenting as high fever with diffuse alveolar hemorrhage and otitis media: A case report
| Autor: | Xiao-Jie Li, Jiang-Hua Liu, Chu-Ting Zhan, Liu Yang, Xiao-Feng Yan |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Diffuse alveolar hemorrhage business.industry General Medicine respiratory system medicine.disease Methylprednisolone Dermatology High fever 03 medical and health sciences 0302 clinical medicine Otitis 030220 oncology & carcinogenesis Case report Medicine 030211 gastroenterology & hepatology Granulomatosis with polyangiitis medicine.symptom business Otitis media Intravenous immunoglobulin medicine.drug |
| Zdroj: | World Journal of Clinical Cases |
| ISSN: | 2307-8960 |
| DOI: | 10.12998/wjcc.v9.i10.2344 |
| Popis: | BACKGROUND Granulomatosis with polyangiitis is a necrotizing inflammation of small and medium-sized vessels accompanied by formation of granuloma, involvement of primary granulomatous upper and lower respiratory tracts, glomerulonephritis, and vasculitis of small vessels. CASE SUMMARY Herein, we described a case of a 52-year-old man admitted with pulmonary nodules and high fever. Autoantibody workup revealed that the patient was positive for c-anti-neutrophil cytoplasmic antibodies and proteinase-3 anti-neutrophil cytoplasmic antibodies. Pulmonary biopsies revealed a local granulomatous structure. The patient received therapy with methylprednisolone and intravenous immunoglobulin, and his clinical symptoms improved. CONCLUSION Intravenous immunoglobulin may act on granulomatosis with polyangiitis similar to immunosuppressants. |
| Databáze: | OpenAIRE |
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