Evolution of Diastolic Dysfunction in Patients with Coronary Slow Flow Phenomenon and Acute Non-ST Segment Elevation Myocardial Infarction
| Autor: | Mahmoud Abdelaziz, Ahmed El Zayat, Ahmed Yousry, Ismail Mohamed Ibrahim |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test business.industry Diastole Slow-Flow Phenomenon Mean age Coronary slow flow Doppler echocardiography medicine.disease Tissue Doppler echocardiography Microvascular dysfunction Internal medicine Cardiology medicine ST segment Diastolic dysfunction Radiology Nuclear Medicine and imaging In patient Original Article Myocardial infarction Non-ST elevation myocardial infarction Cardiology and Cardiovascular Medicine business |
| Zdroj: | Journal of Cardiovascular Imaging |
| ISSN: | 2586-7296 |
| Popis: | BACKGROUND Diastolic function has been reported to be impaired in many patients with coronary slow flow phenomenon (CSFP). CSFP has broad spectrum of clinical presentations, including non-ST elevation myocardial infarction (NSTEMI). We sought to study the short-term evolution of diastolic function in CSFP patients presenting with NSTEMI. METHODS This study included 92 patients with CSFP and acute NSTEMI. Conventional echocardiography Doppler imaging and tissue Doppler echocardiography imaging were used to evaluate diastolic function during index NSTEMI and after 3 months. RESULTS Mean age of study patients was 45.7 ± 6.8 years. The prevalence of diastolic dysfunction (DD) at baseline was 69 patients (75%) and 28 patients (30.4%) at 3 months, p < 0.001. Various diastolic function indices showed significant improvement from baseline to 3 months follow-up. E/Em was 17.32 ± 3.41 at baseline compared to 12.41 ± 5.58 at 3 months, p = 0.039. Septal e' velocity was 5.67 ± 4.56 cm/s at baseline compared to 7.78 ± 3.22 cm/s at 3 months, p = 0.023. Medications used were not significantly different between those with improved versus unimproved DD. CONCLUSIONS Diastolic function seems to improve over short-term follow-up in patients with CSFP presenting with NSTEMI. This could reflect a transient worsening during acute NSTEMI. |
| Databáze: | OpenAIRE |
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