Continued symptomatic improvement three to five years after transmyocardial revascularization with co2laser
| Autor: | Kjell Rootwelt, Svein Blomhoff, Kjell Saatvedt, Kolbjørn Forfang, Lars Aaberge, Michel Abdelnoor |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
medicine.medical_specialty
Ejection fraction SF-36 business.industry Unstable angina medicine.medical_treatment medicine.disease Revascularization Transmyocardial revascularization law.invention Surgery Angina Randomized controlled trial law Heart failure Internal medicine Cardiology Medicine cardiovascular diseases Cardiology and Cardiovascular Medicine business |
| Zdroj: | Journal of the American College of Cardiology. 39:1588-1593 |
| ISSN: | 0735-1097 |
| DOI: | 10.1016/s0735-1097(02)01828-4 |
| Popis: | Objectives The goals of this study were to assess late clinical outcome and left ventricular ejection fraction (LVEF) after transmyocardial revascularization with CO2laser (TMR). Background During the 1990s TMR emerged as a treatment option for patients with refractory angina not eligible for conventional revascularization. Few reports exist on clinical effects and LVEF >3 years after TMR. Methods One hundred patients with refractory angina not eligible for conventional revascularization were block-randomized 1:1 to receive continued medical treatment or medical treatment combined with TMR. The patients were evaluated at baseline and after 3, 12 and 43 (range: 32 to 60) months with end points to angina, hospitalizations due to acute myocardial infarctions or unstable angina, heart failure and LVEF. Mortality was registered and MOS 36 Short-Form Health Survey answered at baseline and after 3, 6 and 12 months. Results Forty-three months after TMR, angina symptoms were still significantly improved, and unstable angina hospitalizations reduced by 55% (p Conclusions Forty-three months after TMR, angina symptoms and hospitalizations due to unstable angina were significantly reduced, heart failure treatment increased and LVEF and mortality were seemingly unaffected. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|