Comparison of pleural effusion between fenestrated and nonfenestrated extracardiac Fontan: A prospective randomized study

Autor:	Vishnubhatla Sreeniwas, Ashish Dutt Upadhyay, Adarsh Paidi, Shiv Kumar Choudhary, Sambhunath Das, Sachin Talwar
Rok vydání:	2020
Předmět:	Male Risk Pulmonary and Respiratory Medicine medicine.medical_specialty Time Factors Cardiovascular pathology Adolescent Pleural effusion 030204 cardiovascular system & hematology Fontan Procedure Tricuspid Atresia Pleural drainage 03 medical and health sciences Postoperative Complications 0302 clinical medicine Primary outcome Recurrence Humans Medicine Prospective randomized study Prospective Studies Child Device Removal business.industry Mean age Length of Stay medicine.disease Surgery Pleural Effusion Treatment Outcome 030228 respiratory system Chest Tubes Female Cardiology and Cardiovascular Medicine business Fenestration Hospital stay
Zdroj:	Journal of Cardiac Surgery. 35:2688-2694
ISSN:	1540-8191 0886-0440
Popis:	Background Fenestration of the baffle/conduit is believed to reduce pleural effusion following the Fontan operation. However, equivocal results have been observed with or without fenestration. This study aims to evaluate the efficacy of fenestration on the amount and duration of pleural effusion following the Fontan operation. Methods About 40 patients undergoing extracardiac Fontan (ECF) were randomized into two groups: one with fenestration (ECF-F; n = 20) or without fenestration (ECF-NF; n = 20). Primary outcome was the amount and duration of pleural effusions. Secondary outcomes were time to removal of the chest tubes, hospital stay, and readmission to the hospital because of recurrent pleural within 30 days of the operation. Results Mean age was 11.5 ± 5.07 (range, 8.7-13.5) years in the ECF-F group and 13.6 ± 0.4 years (range, 10.5-15.5) in the (ECF-NF) group. The total drain output was 7.89 mL/kg/d in ECF-NF compared with 6.9 mL/kg/d in the ECF-group (P = .14). Time for removal of pleural tubes was 14.6 ± 0.95 days in the ECF-NF group compared with 11.6 ± days in the ECF-F group. Total duration of hospital stay was higher but not significant in the ECF-NF group compared with the ECF-F group. Two patients in ECF-NF required readmission to the hospital within 30 days following discharge, while there were no readmissions in the ECF-F group. Conclusion Contrary to the literature, the creation of a fenestration in the ECF circuit was not clearly associated with a reduction in the amount and duration of pleural effusion compared with a non-fenestrated Fontan. These findings may be debatable in high risks versus low risk candidates. However in the present study, in a low risk canditates undergoing the Fontan operation, the daily amount of pleural drainage was no different. Larger studies are needed to confirm these findings.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e365efcef70b88c2087561b6f1e41962 https://doi.org/10.1111/jocs.14886 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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