Emotional and behavioral adjustment in 4 to 11-year-old boys and girls with classic congenital adrenal hyperplasia and unaffected siblings
Autor: | Sharon Neufeld, Carlo L. Acerini, Peter C. Hindmarsh, Debra Spencer, Ieuan A. Hughes, Karson T. F. Kung, Vickie Pasterski, Melissa Hines |
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Přispěvatelé: | Spencer, Debra [0000-0003-0098-5658], Neufeld, Sharon [0000-0001-5470-3770], Acerini, Carlo [0000-0003-2121-5871], Apollo - University of Cambridge Repository |
Jazyk: | angličtina |
Rok vydání: | 2018 |
Předmět: |
Male
congenital hereditary and neonatal diseases and abnormalities Social stigma endocrine system diseases Endocrinology Diabetes and Metabolism Emotions Population Child Behavior BF 030209 endocrinology & metabolism 03 medical and health sciences Child Development 0302 clinical medicine Endocrinology Surveys and Questionnaires Humans Medicine Family Women Child Gonadal Steroid Hormones education Biological Psychiatry Sex Characteristics education.field_of_study Adrenal Hyperplasia Congenital Psychopathology Disorder of sex development Endocrine and Autonomic Systems business.industry Internalizing Siblings Gender Men Strengths and Difficulties Questionnaire Child development Hormones United Kingdom Externalizing Psychiatry and Mental health Prosocial behavior Child Preschool Classic Congenital Adrenal Hyperplasia Female business 030217 neurology & neurosurgery Clinical psychology Sex characteristics |
ISSN: | 0306-4530 |
Popis: | It has been suggested that atypical hormone environments during early development may contribute to subsequent development of psychopathology. Also, it has been suggested that individuals with the autosomal recessive genetic variant, classic congenital adrenal hyperplasia (CAH), might be at increased risk of psychopathology. The present study examined emotional and behavioral adjustment in young children with CAH and their unaffected siblings in the United Kingdom. The parent-reported version of the Strengths and Difficulties Questionnaire (SDQ) was employed to assess adjustment in children aged 4 to 11 years. There were 38 boys with CAH, 43 girls with CAH, 23 unaffected brothers, and 31 unaffected sisters. No differences in emotional or behavioral problems were found between boys or girls with CAH and unaffected same-sex siblings. In addition, affected and unaffected boys in the current sample generally did not differ from boys in the general population. However, compared with girls in the general population, girls with CAH had more difficulties related to conduct problems, hyperactivity/ inattention, and prosocial behavior, and unaffected sisters had more difficulties related to peer problems, conduct problems, and prosocial behavior. These findings suggest that both girls with CAH and unaffected sisters of girls or boys with CAH may be at increased risk of developing behavioral problems. Potential influences related to the early hormone environment, familial process, and social stigma are considered. |
Databáze: | OpenAIRE |
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