Serum and salivary ferritin and Hepcidin levels in patients with chronic periodontitis and type 2 diabetes mellitus
| Autor: | Yan-Zong Yang, Lin-Na Guo, Yun-Zhi Feng |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Adult Male Serum medicine.medical_specialty Saliva endocrine system diseases Hepcidin 03 medical and health sciences 0302 clinical medicine Hepcidins Internal medicine Periodontal Attachment Loss Type 2 diabetes mellitus medicine Humans In patient General Dentistry Aged Aged 80 and over Ferritin medicine.diagnostic_test biology business.industry Dental Plaque Index Type 2 Diabetes Mellitus nutritional and metabolic diseases 030206 dentistry Middle Aged medicine.disease Chronic periodontitis lcsh:RK1-715 030104 developmental biology Endocrinology Clinical attachment loss Diabetes Mellitus Type 2 lcsh:Dentistry Immunoassay Case-Control Studies Chronic Periodontitis Ferritins biology.protein Female Periodontal Index business Research Article |
| Zdroj: | BMC Oral Health BMC Oral Health, Vol 18, Iss 1, Pp 1-9 (2018) |
| ISSN: | 1472-6831 |
| Popis: | Background Iron disorder and abnormal expression of hepcidin play important roles in many diseases, but it is still unclear in chronic periodontitis (CP) and type 2 diabetes mellitus (T2DM). We aimed to assess ferritin and hepcidin levels in serum and saliva of CP patients with or without T2DM. Methods Serum and unstimulated whole saliva samples were collected from 88 participants, who were categorized into 4 groups based on the presence or absence of CP or T2DM. Demographics and general health parameters were recorded. Full-mouth clinical periodontal parameters including probing pocket depth, clinical attachment loss, bleeding index, and plaque index were recorded. Chemiluminescence microparticle immunoassay and enzyme-linked immunosorbent assay were used to detect ferritin and hepcidin concentrations, respectively, in serum and saliva. Results Serum ferritin and hepcidin levels in the CP and CP with T2DM groups were higher than in the control group (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink