Organic mercury compounds: human exposure and its relevance to public health
| Autor: | George R Prince, H. Edward Murray, John F. Risher |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
Preservative
Organomercury Compounds Health Toxicology and Mutagenesis chemistry.chemical_element Food Contamination 010501 environmental sciences Toxicology Risk Assessment 030226 pharmacology & pharmacy 01 natural sciences 03 medical and health sciences chemistry.chemical_compound Ethylmercury 0302 clinical medicine Paint Animals Humans Methylmercury Shellfish 0105 earth and related environmental sciences Inhalation Chemistry Fishes Public Health Environmental and Occupational Health Thimerosal Environmental Exposure Environmental exposure Mercury (element) Environmental chemistry Public Health Merbromin Disinfectants |
| Zdroj: | Toxicology and Industrial Health. 18:109-160 |
| ISSN: | 1477-0393 0748-2337 |
| DOI: | 10.1191/0748233702th138oa |
| Popis: | Humans may be exposed to organic forms of mercury by either inhalation, oral, or dermal routes, and the effects of such exposure depend upon both the type of mercury to which exposed and the magnitude of the exposure. In general, the effects of exposure to organic mercury are primarily neurologic, while a host of other organ systems may also be involved, including gastrointestinal, respiratory, hepatic, immune, dermal, and renal. While the primary source of exposure to organic mercury for most populations is the consumption of methylmercury-contaminated fish and shellfish, there are a number of other organomercurials to which humans might be exposed. The antibacterial and antifungal properties of organomercurials have resulted in their long use as topical disinfectants (thimerosal and merbromin) and preservatives in medical preparations (thimerosal) and grain products (both methyl and ethyl mercurials). Phenylmercury has been used in the past in paints, and dialkyl mercurials are still used in some industrial processes and in the calibration of certain analytical laboratory equipment. The effects of exposure to different organic mercurials by different routes of exposure are summarized in this article. |
| Databáze: | OpenAIRE |
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