Supra-aortic low-dose contrast-enhanced time-resolved magnetic resonance (MR) angiography at 3 T: comparison with time-of-flight MR angiography and high-resolution contrast-enhanced MR angiography
| Autor: | Hyun Seok Choi, Youn-Joo Lee, So-Lyung Jung, Ja-Sung Koo, Kook-Jin Ahn, Bom-yi Kim, Jinhee Jang, Bum-Soo Kim |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Magnetic Resonance Spectroscopy Time Factors media_common.quotation_subject Aortic Diseases Contrast Media Constriction Pathologic Aortography Magnetic resonance angiography medicine.artery medicine Contrast (vision) Humans Radiology Nuclear Medicine and imaging Prospective Studies Prospective cohort study media_common Aged Radiological and Ultrasound Technology medicine.diagnostic_test business.industry Arterial stenosis Magnetic resonance imaging General Medicine Arteries Middle Aged medicine.disease Stenosis Female Radiology Bolus (digestion) business Magnetic Resonance Angiography Circle of Willis |
| Zdroj: | Acta radiologica (Stockholm, Sweden : 1987). 56(6) |
| ISSN: | 1600-0455 |
| Popis: | Background Low-dose, time-resolved, contrast-enhanced, magnetic resonance angiography (TR-CEMRA) has been described previously; however, a comparative study between low dose TR-CEMRA and time-of-flight MRA (TOF-MRA) in the diagnosis of supra-aortic arterial stenosis has not yet been published. Purpose To demonstrate the feasibility and effectiveness of low-dose TR-CEMRA compared with TOF-MRA, using high-resolution contrast-enhanced MRA (HR-CEMRA) as the reference standard. Material and Methods This prospective study consisted of 30 consecutive patients. All patients underwent TOF-MRA of the neck and circle of Willis and supra-aortic HR-CEMRA, followed by supra-aortic low-dose TR-CEMRA. Gadoterate meglumine (Gd-DOTA, Dotarem®, Guerbet, Roissy CdG Cedex, France) was injected at a dose of 0.1 mmol/kg for HR-CEMRA, followed by a 0.03 mmol/kg bolus for low-dose TR-CEMRA. Three readers evaluated the assessibility and image quality, and then two readers classified each stenosis into the following categories: normal (0–30%), mild stenosis (31–50%), moderate (51–70%), severe (71–99%), and occlusion. Results TR-CEMRA and HR-CEMRA showed a greater number of assessable arterial segments than TOF-MRA ( P Conclusion Low-dose TR-CEMRA is feasible and effective in the diagnosis of supra-aortic arterial stenosis, and could be more useful option than TOF-MRA. |
| Databáze: | OpenAIRE |
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